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Found 2,831 clinical trials

G Guillaume Taieb, MD

Biomarkers in Polyradiculoneuropathies

The nodes of Ranvier contain ion channels that enable the rapid propagation of the nerve impulse. Cell adhesion molecules and glycolipids play an important role in the formation of the nodes of Ranvier. Antibodies against glycolipids are detected in half of patients with Guillain-Barr syndrome, an acute inflammatory neuropathy affecting …

18 years and older All Phase N/A
D Di Dong, Ph.D.

Classification of Benign and Malignant Lung Nodules Based on CT Raw Data

The employ of medical images combined with deep neural networks to assist in clinical diagnosis, therapeutic effect, and prognosis prediction is nowadays a hotspot. However, all the existing methods are designed based on the reconstructed medical images rather than the lossless raw data. Considering that medical images are intended for …

18 years and older All Phase N/A
M Mandy Spaltman

PJ-011726 IntelliSpace Cognition MCI Study

This study aims to create a reference database of digital cognitive assessment data in combination with neuroimaging data of patients with mild cognitive impairment. The investigators will explore and derive correlations between parameters from routine MRI images and brain volumetric analysis and the digital cognitive data to identify parameters that …

50-80 years All Phase N/A
T Tania Claeys, Dr.

Detection of Metabolite Biomarkers for the Early Diagnosis and Prognosis of Cow's Milk Allergy in Children

In this study, fecal and urine samples will be collected from children diagnosed with : IgE mediated cow's milk allergy, suspected of a cow's milk allergy, but with negative diagnosis IgE mediated food allergy other than cow's milk healthy brothers and sisters of the first three groups A subset of …

5 years and younger All Phase N/A
E Eric TELLIER, Dr

Pulse Oximetry in Healthy SubjEcts ImmergeD in OceaN.

Drowning is the 3rd leading cause of accidental death in the world. One of the tools used by lifeguards to help ER assess gravity, is pulse oximetry. Its measure is variable even in optimal condition and its accuracy can be altered by factors specific to the patient and by environmental …

18-75 years All Phase N/A
J Jennifer Victory, RN

Feasibility of Non-Operative Management of Rectal Cancer in a Rural Population

This is an observational research study. Patients with rectal cancer can choose different courses of treatment. This study will follow these patients over the course of approximately six years, depending on their treatment. Patients will be monitored through clinic visits and survey assessments to see how they do, how they …

18 years and older All Phase N/A
B Benjamin Jones, MRCOG

INvestigational Study Into Transplantation of the Uterus

Observational study on cohort of 10 women undergoing uterine transplantation using deceased donors

24-38 years Female Phase N/A
B Belaïd BOUHEMAD

Interest of a Period of Fasting Before Extubation in Resuscitation Patients

Orotracheal extubation in resuscitation is a situation in which there is an elevated risk of inhalation. In resuscitation, enteral nutrition that is administered in a continuous flow is likely to accumulate in the stomach. Gastric motility in resuscitation patients may be impaired for many reasons: Iatrogenic: Catecholamines, sedatives and opioids …

18 years and older All Phase N/A
P Paul LEGENDRE, MD

MPA AUC Monitoring in Patients Receiving MMF for Diffuse Cutaneous or Pulmonary Involvement in Systemic Sclerosis

To define a target value of AUC MPA to improve the modified Rodnan score and / or respiratory impairment (DLCO or FVC) at one year in patients receiving MMF for the treatment of diffuse cutaneous or interstitial lung damage of systemic sclerosis.

18 years and older All Phase N/A
J Jennifer Scovotti, MA

Postoperative Neurocognitive Disorders

The purpose of this study is to examine the mechanisms of brain injury contributing to postoperative neurocognitive disorders (PNCD) in an at-risk population (obstructive sleep apnea (OSA)) undergoing surgery. The investigators will enroll 50 OSA patients scheduled for surgery. All patients will have a brain scan (fMRI) within five days …

40-75 years All Phase N/A

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