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Found 1399 clinical trials
Convalescent Plasma for the Treatment of Patients With Severe COVID-19 Infection

This is a multicenter, Phase 2 study, to assess the efficacy of the treatment with convalescent plasma in patients with severe COVID-19 infection.

acute respiratory syndrome (sars)
shock
covid-19
FIO2
organ failure
  • 0 views
  • 19 Feb, 2024
  • 6 locations
A Study to Evaluate the Safety Tolerability and Pharmacokinetics of Orally Inhaled Aerosolized Hydroxychloroquine Sulfate in Healthy Adult Volunteers

This study is 'A Randomized Phase 1 Double Blind Placebo Controlled, Single-Dose, Dose-Escalation Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Orally Inhaled Aerosolized Hydroxychloroquine Sulfate in Healthy Adult Volunteers.' The primary objectives are as follows: To assess the safety and tolerability of AHCQ administered as a single dose …

chloroquine
body mass index
hydroxychloroquine
nasopharyngeal swab
pulse oximetry
  • 0 views
  • 19 Feb, 2024
  • 1 location
Metformin for Abdominal Aortic Aneurysm Growth Inhibition

A multi-centre population-based open-label randomized controlled trial with allocation concealment and blinded outcome assessment will examine if up to 2g metformin daily slows AAA growth in patients with small AAAs who do not have diabetes.

aaas
abdominal aortic aneurysm
aortic aneurysm
metformin
diabetes
  • 0 views
  • 19 Feb, 2024
  • 1 location
Outcome of Facial Palsy Following Rehabilitation

Retrospective case series,the aim of this study is to assess the outcome and rate of complications in patients with facial palsy following rehabilitation, a retrospective study.

bell's palsy
peripheral facial palsy
  • 0 views
  • 19 Feb, 2024
  • 1 location
Multicenter Perspective Study: Clinical Evaluation of the Persona MC With Preservation or Sacrifice of the PCL

Prospective, multicenter study on the Total Knee Prosthesis available on the market "Persona Medial Congruent knee". Primary endpoint -Evaluation of the survival of the implant after 5 years of follow-up Secondary endpoints Evaluation of the survival of the implant at 10 years of follow up. Evaluation of clinical and radiographic …

osteoarthritis
knee arthroplasty
knee pain
arthritis
avascular necrosis
  • 0 views
  • 19 Feb, 2024
  • 1 location
Nivolumab Ipilimumab and Chemoradiation in Treating Patients With Locally Advanced Pancreatic Cancer.

Pancreatic ductal adenocarcinoma (PDAC) remains a dreadful disease due to its often advanced stage at diagnosis and poor sensitivity to chemotherapy. A locally unresectable tumor (locally advanced pancreatic cancer (LAPC)) is present in 30% of the cases and is defined as a surgically unresectable tumor encasing the adjacent arteries [celiac …

cancer
pancreatic ductal adenocarcinoma
pdac
immunosuppressive agents
carcinoma
  • 0 views
  • 24 Nov, 2025
  • 1 location
Music as Analgesia During Neonatal Circumcision

Neonatal circumcision is one of the most frequently performed and more painful procedures. Sharara et al (2017) showed the combination of EMLA + Sucrose + Ring Block provides the highest standard of pain management. A combination which has been adopted by practitioners who perform circumcisions at the normal nursery at …

emla
analgesia
  • 0 views
  • 19 Feb, 2024
  • 1 location
ACX-362E [Ibezapolstat] for Oral Treatment of Clostridioides Difficile Infection

This trial will evaluate the safety, efficacy, pharmacokinetics, fecal concentrations, and fecal microbiome effects of ACX-362E [ibezapolstat] in patients with C. difficile infection (CDI). The current record applies only to Segment 2A, primary completion date August 2020.

white blood cell count
aspart
stool test
diarrhea
  • 0 views
  • 19 Feb, 2024
  • 6 locations
The Effect of High Protein and Early Resistance Exercise Versus Usual Care in Critically Ill Patients (EFFORT-X Trial)

This is a 2-arm, parallel-group, randomized controlled trial that investigates the effect of combined high protein and early resistance exercise versus usual care on muscle mass, quality and strength, clinical outcomes, functional outcomes and quality of life in mechanically ventilated critically ill patients

  • 0 views
  • 19 Feb, 2024
  • 1 location
Effect of Nervous System Mobilization on Athletes' Performance

This study aims to compare the effects of two diferente doses of nervous system mobilization on athletes performance.

nervousness
nervous system
  • 0 views
  • 19 Feb, 2024
  • 1 location