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Found 260 clinical trials
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Tofacitinib for Immune Skin Conditions in Down Syndrome

People with Down syndrome (DS) display widespread immune dysregulation, including several immune skin conditions. This study hypothesizes that pharmacological inhibition of the increased interferon (IFN) signaling seen in DS is safe and could improve associated skin conditions. The study evaluates the safety and efficacy treatment with Tofacitinib, an FDA-approved drug …

antimicrobials
antibiotics
alopecia areata
unbalanced translocation
atopic diathesis
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  • 19 Feb, 2024