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Found 26006 clinical trials
Systematic Radioiodine Administration (3.7 GBq I131 After rhTSH) Versus Decision of Radioiodine Treatment Guided by a Post-operative Work-up

This trial is comparing two strategies in intermediate-risk differentiated thyroid cancer patients: Systematic radioiodine administration (3.7 GBq I131 after rhTSH) versus decision of radioiodine treatment guided by a post-operative work-up based on serum Tg values and diagnostic RAI scintigraphy

vascular invasion
neck dissection
thyroidectomy
thyrotropin alpha
cancer
  • 0 views
  • 19 Feb, 2024
  • 1 location
Safety and Efficacy of BCMA-Targeted CAR-T Therapy for Relapsed/Refractory Multiple Myeloma

This is a single arm study to evaluate the efficacy and safety of BCMA-targeted CAR-T cells therapy for patients with relapsed/refractory Multiple Myeloma.

renal function
multiple myeloma
cellular therapy
remission
oxygen saturation
  • 0 views
  • 19 Feb, 2024
  • 1 location
BCMA-Targeted CAR-T Cell Therapy for Relapsed/Refractory Multiple Myeloma

This is a single arm study to evaluate the efficacy and safety of BCMA-targeted CAR-T cells therapy for patients with relapsed/refractory Multiple Myeloma.

t cell therapy
renal function
multiple myeloma
cellular therapy
remission
  • 0 views
  • 24 Nov, 2025
  • 1 location
LYT-100 in Healthy Volunteers and BCRL

Part 1 is a multiple ascending dose trial in healthy volunteers (HV) of LYT-100 to determine safety, tolerability, and pharmacokinetic (PK) profile under fed conditions. Part 2 is a single dose safety, tolerability, and PK trial in HV of LYT-100 under fasted conditions. Part 3 is a trial of up …

secondary lymphedema
cancer surgery
breast cancer
cancer
carcinoma
  • 0 views
  • 19 Feb, 2024
  • 1 location
Concurrent Chemoradiotherapy After Endoscopic Resection for Stage I Esophageal Carcinoma

This is a prospective single-arm study of endoscopic resection (ER) following concurrent chemoradiotherapy for stage I esophageal squamous cell carcinoma, to find if the treatment combination is useful by assessing its safety and efficacy.

endoscopic ultrasound
cancer
carcinoma
metastasis
blood pregnancy test
  • 0 views
  • 19 Feb, 2024
  • 1 location
Spermatogonial Stem Cell (SSC) Transplant and Testicular Tissue Grafting

Spermatogonial stem cell transplantation through ultrasound guided rete testis injection and testicular tissue grafting will be performed for participants who have frozen testicular tissue prior to gonadotoxic therapy. The purpose of this study is to test the safety and feasibility of these transplant technologies and restore fertility for these participants.

anesthesia
infertility
autograft
testis
testicular
  • 0 views
  • 19 Feb, 2024
  • 1 location
Everolimus Plus Mycophenolic Acid for Kidney Preservation in Liver Transplant Recipients With Impaired Kidney Function

Secondary Aims Compare the efficacy of Everolimus plus Mycophenolate Mofetil versus Tacrolimus plus Mycophenolate Mofetil therapy as measured by the following: Biopsy-confirmed acute rejection Hyperlipidemia Proteinuria % regulatory T-cells in circulation NODAT [New Onset Diabetes mellitus After Transplant], hypertension and malignancy Tolerance measured by gene profiling at year 1, 2 …

renal function test
glomerular filtration rate
everolimus
cancer
renal failure
  • 0 views
  • 19 Feb, 2024
  • 1 location
Improving Survivorship Care for Older Adults After Chemotherapy

The researchers want to find out if older adults receiving a survivorship care plan followed by a geriatric assessment visit improves quality of life and satisfaction with care compared to receiving only a survivorship care plan for older adults who have completed chemotherapy for cancer treatment.

  • 0 views
  • 19 Feb, 2024
  • 1 location
the Efficacy and Safety of 5-HT3 Receptor Antagonist Dexamethasone or Megestrol Acetate Dispersible Tablets in the Control of Nausea and Vomiting Induced by Highly Emetogenic Chemotherapy

To compare the efficacy and safety of megestrol acetate dispersible tablets combined with 5-HT3 receptor antagonist and dexamethasone triple antiemetic regimen and 5-HT3 receptor antagonist and dexamethasone combined antiemetic regimen in the control of CINV induced by hyperemetic chemotherapy.

emetic
nausea
dexamethasone
antiemetic
emetics
  • 0 views
  • 19 Feb, 2024
  • 1 location
Sacituzumab Govitecan +/- Pembrolizumab in Metastatic TNBC

This research study involves testing the safety and efficacy of an investigational intervention for patients with triple-negative breast cancer (TNBC) that has spread, or metastasized, to other parts the body and is PD-L1-negative. The names of the study interventions involved in this study are: Sacituzumab govitecan (IMMU-132) Pembrolizumab (Keytruda; MK-3475)

breast cancer
neuropathy
brain metastases
measurable disease
bisphosphonate
  • 8 views
  • 19 Feb, 2024
  • 1 location