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Found 26011 clinical trials
Altered Tumor Oxygenation by Metformin a Potential Step in Overcoming Radiotherapy Resistance in LACC

Poor tumor oxygenation (hypoxia) is an established negative prognostic and predictive factor in locally advanced cervical cancer (LACC). Hypoxia-modifying measures implemented in the clinic are lacking.

metformin
cervical neoplasm
cisplatin
hypoxia
renal function
  • 0 views
  • 19 Feb, 2024
  • 1 location
RISI in the Treatment of Recurrent Metastatic SCC of Thoracic Inlet Lymph Nodes

The malignant tumor at the thoracic entrance is difficult to be surgically removed, and radiotherapy or radiotherapy based comprehensive treatment is often chosen at the initial diagnosis.

anticoagulants
coagulopathy
squamous cell carcinoma
metastatic squamous cell carcinoma
solid tumors
  • 0 views
  • 19 Feb, 2024
  • 1 location
Lenvatinib and Pembrolizumab Before Surgery for the Treatment of Locally Advanced Non-Metastatic Kidney Cancer

Lenvatinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread.

anticoagulants
beta human chorionic gonadotrophin
kidney cancer stage iii
pembrolizumab
chorionic gonadotropin
  • 8 views
  • 19 Feb, 2024
  • 1 location
A Trial Aiming to Assess the Safety and Activity of the Combination of Cabozantinib Plus Lanreotide in GEP and NET

A Phase II trial aiming to assess the safety and activity of the combination of cabozantinib plus lanreotide in gastroenteropancreatic (GEP) and thoracic neuroendocrine tumor (NET): The LOLA trial

coronary artery bypass graft surgery
renal function
arterial dissections
congestive heart failure
skin cancer
  • 0 views
  • 19 Feb, 2024
  • 1 location
IBI3014 in Participants With Unresectable Locally Advanced or Metastatic Solid Tumors

This is a phase 1/2 multicenter, multi-regional, open-label, first-in-human study of IBI3014 in participants with unresectable locally advanced or metastatic solid tumors.

  • 0 views
  • 22 Aug, 2025
  • 2 locations
Cetuximab After Immunotherapy for the Treatment of Head and Neck Squamous Cell Cancer

This is a Phase II treatment, non-randomized, open label clinical trial to study the efficacy of the Cetuximab when administered as single agent in recurrent/ metastatic head and neck squamous cell carcinoma after the failure or intolerance of immuno-oncology or immuno-oncology combined with chemotherapy.

cancer
squamous cell carcinoma
recurrent head and neck squamous cell carcinoma
head and neck cancer
cancer of the head
  • 0 views
  • 19 Feb, 2024
  • 1 location
A First-in-human Study Using BDC-1001 in Advanced and HER2-Expressing Solid Tumors

A first-in-human study using BDC-1001 in HER2 expressing advanced malignancies

cancer
pembrolizumab
exhausted
gene amplification
gastric tumor
  • 0 views
  • 19 Feb, 2024
  • 7 locations
A Study of SY 5609 a Selective CDK7 Inhibitor in Advanced Solid Tumors

This is a dose escalation study and will be the first to administer SY-5609 alone to humans with select advanced solid tumors and in combination with Fulvestrant to patients with HR positive, HER2-negative breast cancer.

solid tumour
human chorionic gonadotropin
hair thinning
health screening
her2/neu-negative breast cancer
  • 0 views
  • 19 Feb, 2024
  • 5 locations
Clindamycin and Triamcinolone in People With Glioblastoma to Prevent Skin-Related Side Effects of Tumor Treating Fields

The participants are being treated with Tumor Treating Fields (TTFields) for malignant glioma, and this type of treatment may cause skin-related side effects. This study will test whether using clindamycin and triamcinolone topical lotions can prevent skin-related side effects of TTFields.

triamcinolone
tumor treating fields therapy
glioblastoma multiforme
ttfields
triamcinolone topical
  • 0 views
  • 19 Feb, 2024
  • 7 locations
Dose Reduction of Postoperative Radiation for Soft Tissue Sarcoma of the Arms and Legs

The investigators are doing this study to find out whether lowering the dose of postoperative radiation therapy and targeting a smaller area of tissue for treatment is as effective as the standard dose and volume of radiation therapy to control soft tissue sarcoma after surgery. They also want to find …

soft tissue sarcoma
serum pregnancy test
sarcoma of the extremity
primary tumor
sarcoma
  • 0 views
  • 19 Feb, 2024
  • 7 locations