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Found 259 clinical trials
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Camrelizumab Combined With Apatinib Mesylate for Head and Neck Squamous Cell Carcinoma

This is a prospective, open-labelled study to evaluate the efficacy and safety of camrelizumab combined with apatinib mesylate in the induction treatment of patients with locally advanced head and neck squamous cell carcinoma who were judged surgically unresectable or appropriate for non-surgical definitive therapy. The objective response rate (ORR) and …

squamous cell carcinoma of head and neck
apatinib
measurable disease
carcinoma
definitive treatment
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  • 19 Feb, 2024
  • 1 location
Imaging of Tumour Microenvironment in Patients With Oropharyngeal Head and Neck Squamous Cell Carcinoma Using RGD PET/CT Imaging

Known risk factors inducing squamous cell carcinomas of the head and neck are tabacco and alcohol intake. However, the incidence of human papillomavirus (HPV) related oropharyngeal carcinomas is increasing. It is known that HPV+ and HPV- tumors have a different reaction to (chemo)radiotherapy. The exact mechanisms underlying these differences is …

chemoradiotherapy
carcinoma
immunohistochemistry
pet/ct scan
tobacco products
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  • 19 Feb, 2024
  • 1 location
Hypofractionated Radiotherapy in Elderly Patients With Head & Neck Squamous Cell Carcinoma

The purpose of this research study is to investigate a shorter radiation treatment schedule for head and neck cancers in patients 70 years of age and older. Standard radiation treatment for head and neck patients normally requires that the patient travel to the hospital daily for 6-7 weeks to receive …

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  • 19 Feb, 2024
  • 4 locations
Phase II Study for Combination of Camrelizumab and SBRT in the First-line Treatment for R/M HNSCC

This study is a prospective, single-center, open-label, phase II clinical study for patients with recurrent or metastatics quamous cell carcinoma of the head and neck.

squamous cell carcinoma of head and neck
stereotactic body radiation therapy
measurable disease
carcinoma
anticoagulants
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  • 19 Feb, 2024
  • 1 location
HYPORT: A Phase I/II Study of Hypofractionated Post-operative Radiation Therapy for Head and Neck Cancer

There is a strong radiobiological and economic rationale for hypofractionated radiation therapy in head and neck cancer. Phase 1 of the trial aims to assess the acute toxicity and tolerability of hypofractionated radiation therapy in the post-operative setting, and to determine the dose/fractionation for Phase 2. Phase 2 aims to …

psychiatric disorder
carcinoma
intensity-modulated radiation therapy
congestive heart failure
head and neck cancer
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  • 19 Feb, 2024
  • 1 location