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Found 254 clinical trials
Future of Colorectal Cancer Surgery

Colorectal cancer is the third most common cancer in the UK and Ireland, it is the second commonest cancer in both men and women. Very often the diagnosis is made by either endoscopy/colonoscopy and the surgical treatment is carried out by a minimally invasive approach ("Keyhole"surgery). Tissue samples gathered by …

liver function tests
cancer surgery
cancer resection
rectal carcinoma
colorectal cancer
  • 0 views
  • 19 Feb, 2024
Evaluating the Role of Inflammation in Neonatal Epileptogenesis

The purpose of this study evaluate the relationship between inflammation and epilepsy in neonates with seizures after birth.

seizure
eeg monitoring
acute brain injury
encephalopathy
epilepsy
  • 0 views
  • 19 Feb, 2024
COVID-19 in Cancer Patients: Evaluation of Clinical Course and Impact on Oncological Care Including Biobanking

The COVIDHELP study will prospectively evaluate the yet unknown clinical course of the COVID-19 infection in cancer patients and document the impact of potential infrastructural limitations on cancer care of COVID-19 positive patients. All patients consenting will provide peripheral blood samples for prospective biobanking with the aim of investigating immune …

covid-19
cancer
cancer care
  • 0 views
  • 19 Feb, 2024
Long-Term Follow Up of CLN6 Batten Disease Subjects Following Gene Transfer

This is a long-term safety and efficacy study in subjects with CLN6 Batten disease who previously received a single intrathecal administration of AT-GTX-501.

batten
neuronal ceroid lipofuscinosis
ceroid lipofuscinosis
gene therapy
cln6
  • 0 views
  • 19 Feb, 2024
Assessment of Olfactory Dysfunction in SARS CoV-2 (COVID-19) Infection

This study is designed to investigate the acuity of olfactory dysfunction in COVID-19 positive patients in the United Kingdom. In particular defining severity with objective testing and determining if this has any predictive value on the outcome of the SARS CoV-2 infection. In addition, this study will strive to determine …

SARS
covid-19
acute respiratory syndrome (sars)
  • 0 views
  • 19 Feb, 2024
Sedentary Behavior in Older Women With and Without Type 2 Diabetes

Sedentary behavior has been linked to cardiovascular morbidity and mortality, and is particularly common in older adults with type 2 diabetes. The purpose of this observational, mixed-methods study is to better understand the relationship between prolonged sedentary behavior and cardiovascular and metabolic health in older women.

nephropathy
peripheral artery disease
heart surgery
cardiovascular morbidity
metformin
  • 0 views
  • 19 Feb, 2024
Determinants of SARS-COV2 (COVID-19) Persistence After Convalescence

The 2019-2020 COVID-19 pandemic is the largest outbreak in recent history. It is not known how long after someone gets sick with COVID-19 and recovers that they can still infect other people. It is also not known how quickly people make antibodies against the virus, which help clear infection from …

acute respiratory syndrome (sars)
fever
immunoglobulins
convalescence
cough
  • 0 views
  • 19 Feb, 2024
Preoperative Shielding and N/T RT-PCR Swabbing for Elective Cancer Surgery

trial to assess the effectiveness of pre-operative screening for COVID-19 in patients undergoing elective cancer surgery.

covid-19
cancer surgery
cancer
  • 0 views
  • 19 Feb, 2024
The Assessment Of Myocardial Viability Based On CTA/MRI Hybrid Models

The aim of HYBRIDHEART study is to develop new imagistic prototype for a complex evaluation of the myocardial viability by superposing computed tomographic angiographic polar maps of the myocardium with magnetic resonance imaging contractile maps in subjects who suffered an acute myocardial infarction. Moreover, the study will evaluate the association …

MRI
myocardial fibrosis
infarct
myocardial infarction
stemi
  • 0 views
  • 19 Feb, 2024
Prognostic Factors to Regain Consciousness

The study aims to identify factors that predict the medium and long-term outcome of patients with disorders of consciousness (DOC) undergoing early neurological rehabilitation. In this prospective, observational study, 130 DOC patients are going to be included (36 months). At study entry, different routine data, disease severity and functional status …

hypoxia
neurological rehabilitation
traumatic brain injury
coma
stroke
  • 0 views
  • 19 Feb, 2024