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Found 300 clinical trials
Safety and Immunogenicity Study of GX-19 a COVID-19 Preventive DNA Vaccine in Healthy Adults

The objective of our study is to evaluate safety, tolerability, and immunogenicity of COVID-19 preventive DNA vaccine in healthy volunteers.

covid-19
body mass index
dna vaccine
  • 0 views
  • 19 Feb, 2024
  • 1 location
Clinical Trial of YH25448(Lazertinib) as the First-line Treatment in Patients With EGFR Mutation Positive Locally Advanced or Metastatic NSCLC (LASER301)

This Phase III study will be conducted to evaluate the efficacy and safety of YH25448 as first-line treatment in locally advanced or metastatic Non-small Cell Lung Cancer (NSCLC) patients with EGFR mutations

measurable disease
lung adenocarcinoma
gefitinib
lazertinib
EGFR
  • 0 views
  • 19 Feb, 2024
  • 29 locations
Postprandial Effects of Functional Bread

This study investigates whether bread with added galactomannan, a soluble fiber, can reduce the postprandial glucose response in healthy overweight adults.

  • 0 views
  • 19 Feb, 2024
  • 1 location
ACX-362E [Ibezapolstat] for Oral Treatment of Clostridioides Difficile Infection

This trial will evaluate the safety, efficacy, pharmacokinetics, fecal concentrations, and fecal microbiome effects of ACX-362E [ibezapolstat] in patients with C. difficile infection (CDI). The current record applies only to Segment 2A, primary completion date August 2020.

white blood cell count
aspart
stool test
diarrhea
  • 0 views
  • 19 Feb, 2024
  • 6 locations
NasoShield in Healthy Adults to Study Safety and Immunogenicity

The purpose of this study is to evaluate the safety for up to two doses of NasoShield, to determine if antibodies that protect against anthrax are formed after treatment with NasoShield, and to determine whether the formation of these antibodies are affected by different positions of administration.

vasectomy
intrauterine device (iud)
oophorectomy
hysterectomy
tubal ligation
  • 0 views
  • 19 Feb, 2024
  • 1 location
Study of the Efficacy and Safety of Intravenous Pamrevlumab in Hospitalized Patients With Acute COVID-19 Disease

This is a Phase 2 trial to evaluate the efficacy and safety of intravenous (IV) infusions of pamrevlumab as compared to placebo in hospitalized subjects with acute COVID-19 disease.

extracorporeal membrane oxygenation
SARS
mechanical ventilation
capillary oxygen saturation
pneumonia
  • 0 views
  • 19 Feb, 2024
  • 1 location
Effect of Cassia Cinnamon on Arterial Stiffness Parameters in Patients With Type 2 Diabetes Mellitus

Type 2 diabetes mellitus is considered a serious public health problem that has been raising worldwide. In Mexico, it is an important cause of morbi - mortality and its characterized by hyperglycemia that promotes an increase of cardiovascular risk through the impairment of arterial stiffness and endothelial function, which, in …

  • 0 views
  • 19 Feb, 2024
  • 1 location
A First-in-human Study to Assess the Safety Tolerability Pharmacokinetics and Pharmacodynamics of AZD2373 After Single Dose Administration in Healthy Male Subjects of African Ancestry.

This is a Phase 1 study to assess the the safety, tolerability and pharmacokinetics (PK) of AZD2373, following subcutaneous (SC) administration of single ascending doses (SAD) of AZD2373 in healthy male subjects of African ancestry.

body mass index
  • 0 views
  • 19 Feb, 2024
  • 1 location
A Study of LAM-002A for the Prevention of Progression of COVID-19

This is a clinical trial to evaluate the efficacy of LAM-002A compared to placebo treatment in adults with a confirmed SARS-CoV-2 infection who are receiving standards supportive care in an outpatient setting.

  • 0 views
  • 19 Feb, 2024
  • 1 location
Morphological Parameters of In-stent RESTenosis Assessed and Identified by OCT

The statistical risk of intrastent stenosis has fallen considerably with the emergence of latest generation coated stents (drug-eluting stents: DES). The number and clinical lifespan of stents implanted over the last twenty-five years, however, explain the fact that restenosis remains a not unusual clinical problem which is expressed as a …

  • 0 views
  • 19 Feb, 2024
  • 1 location