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Found 240 clinical trials
Early Environmental and Maternal Determinants of Airway Inflammation in Wheezing Disorders in Infants

This study collects data on microbiological, genetic and environmental factors, as well as lung function parameters (e.g. spirometry, body plethysmography, lung-MRI) to assess the complex interaction of predisposing risk factors for impaired lung development and respiratory diseases.

diabetes
lung disease
social interactions
social interaction
  • 0 views
  • 19 Feb, 2024
Registry of Asthma Patients Initiating DUPIXENT

The primary objective of the study is to characterize the patients who initiate treatment for asthma with DUPIXENT in a real-world setting. The secondary objectives of the study are: To characterize real-world use patterns of DUPIXENT for asthma To assess the long-term effectiveness of DUPIXENT in asthma patients in a …

  • 0 views
  • 19 Feb, 2024
Asthma Research in Children and Adolescents

The purpose of this study is to assess the evolution of disease control, health-related quality of life, and the risk of severe asthma exacerbations in children and adolescents with persistent asthma in Spain at short, mid and long-term follow-up. Patient-reported information in this project is collected by computer assisted telephone …

corticosteroids
inhalation technique
computer assisted
asthma
  • 0 views
  • 19 Feb, 2024
A Study of Patients With Chronic Disease

TARGET-RWE is a 10-year, international, longitudinal, observational study of patients with chronic disease designed to specifically address important clinical questions that remain incompletely answered from registration trials. The protocol will follow a master protocol design in which a shared study infrastructure supports progressive development of the registry across the spectrum …

chronic disease
a 10
  • 0 views
  • 19 Feb, 2024
Prospective Longitudinal Observational Research in Atopic Dermatitis

Atopic dermatitis (AD) is a frequent chronic relapsing inflammatory skin disorder, characterized by intensely itchy eczema. AD usually starts within the first 2 years of life. In 30 - 60% of children, inflammation spreads onto other body surfaces such as the gastrointestinal tract, the respiratory tract, and the conjunctives within …

dermatitis
atopy
food allergy
allergic rhinitis
rhinitis
  • 0 views
  • 19 Feb, 2024
Pharmacokinetics Pharmacodynamics and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

The study investigators are interested in learning more about how drugs, that are given to children by their health care provider, act in the bodies of children and young adults in hopes to find the most safe and effective dose for children. The primary objective of this study is to …

acute respiratory syndrome (sars)
SARS
  • 0 views
  • 19 Feb, 2024
The Multi-Ethnic Lifestyle Study

The study design is cross-sectional using a self-completion questionnaire in an English speaking multi-ethic population within Leicester and Leicestershire. The study will adopt a convenient and purposive sampling recruitment strategy across a variety of settings within Leicestershire to facilitate recruitment of a wide range of participants.

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  • 19 Feb, 2024
Asthma: Phenotyping EXacerbations

The main outcomes of this study are to establish a cohort of well-phenotyped asthma patients with a recent history of an exacerbation. We aim to describe exacerbation profiles (phenotypes) of the cohort in terms of inflammatory/biomarker profile and bacterial/viral infection status and to compare these with exacerbation events in the …

corticosteroids
skin prick
maintenance therapy
prick skin
spirometry
  • 0 views
  • 19 Feb, 2024
Asthma: Phenotyping Exacerbations 2

The main outcomes of this study are to establish a cohort of well-phenotyped asthma patients with a recent history of an exacerbation. We aim to describe exacerbation profiles (phenotypes) of the cohort in terms of inflammatory/biomarker profile and bacterial/viral infection status and to compare these with exacerbation events in the …

corticosteroids
skin prick
maintenance therapy
prick skin
spirometry
  • 0 views
  • 19 Feb, 2024
Childhood Allergy and the Neonatal Environment

The purpose of this research study is to study the relationship between childhood asthma, allergies, and early-life environmental factors that may cause childhood asthma and allergies. Previous birth cohort studies have found early-life environmental factors such as allergies, pollutants, viruses and bacteria have all contributed to the development of asthma

hay fever
rhinitis
pollen allergy
allergic rhinitis
asthma
  • 0 views
  • 19 Feb, 2024