Found 255 clinical trials
Open Label Dose Escalation Study for the Safety and Efficacy of STP705 in Adult Patients With isSCC
This is an open label, dose escalation study to evaluate the safety and efficacy of intralesional injection of STP705 in adult patients with Cutaneous Squamous Cell Carcinoma in situ (isSCC, Bowen's disease). The purpose of this trial is to evaluate the safety, tolerability and efficacy of various doses of STP705 …
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- 19 Feb, 2024
- 1 location
Spacer Graft Study (abc)
To determine which of three types of spacer grafts (hard palate vs autologous ear cartilage vs Enduragen) are the most effective in lower eyelid retraction repair outcomes as measured by MRD2 (margin to reflex distance 2)
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- 14 May, 2025
- 1 location
Ultrasound Features of Dupuytren's Disease (Micro in DD)
Dupuytren's disease (DD) is a benign and progressive condition that affects the palmar aponeurosis with a very high global incidence. It can result in significant loss of hand function or can inhibit an individual's daily activities or work. Current diagnostics rely on Range Of Motion (ROM) measurements and clinical expertise, …
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- 07 May, 2025
- 1 location
Individualized Brain Stimulation to Improve Mobility in Alzheimer's Disease
The objective of this study is to conduct a pilot, randomized sham-controlled trials to determine the feasibility and effects of a 10-session personalized tDCS intervention targeting the left dorsolateral prefrontal cortex on cognitive function, dual task standing and walking, and other metrics of mobility in 24 older adults with mild …
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- 19 Feb, 2024
- 1 location
Early Environmental and Maternal Determinants of Airway Inflammation in Wheezing Disorders in Infants
This study collects data on microbiological, genetic and environmental factors, as well as lung function parameters (e.g. spirometry, body plethysmography, lung-MRI) to assess the complex interaction of predisposing risk factors for impaired lung development and respiratory diseases.
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- 19 Feb, 2024
- 1 location
Skin Biophysical Measures for Assessing Head and Neck Cancer-Related External Lymphedema
Selected measurements in healthy persons of skin tissue dielectric constant as reference values for subsequent use to evaluate patients with head and neck lymphedema.
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- 19 Feb, 2024
- 1 location
Sample Collection for Systems Evaluation of Patients With Unknown or Incompletely Characterized Immune Defects
These samples may be from biopsies, endoscopies, or other procedures. Some participants may have optional skin punch biopsies. For this, their skin is numbed. Then a tool removes 1 or 2 small pieces of skin from the forearm or thigh. Participants medical records will be checked to see if they …
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- 19 Feb, 2024
- 1 location
GSD IX Natural History Study
Participant's medical charts will be continually reviewed for the duration of the study. If a liver, muscle or skin biopsy sample has been collected, a piece of the sample may be requested and stored for research purposes.
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- 19 Feb, 2024
- 1 location
Observational Study in Diagnosed Patients COVID-19 Supported on an Outpatient Basis. (COVID-PSL)
Different symptoms may appear: fever, cough, asthenia, dyspnea, gastrointestinal forms, anosmia and / or ageusia, skin involvement, etc. Given the novelty of this infection, several questions remain: What are all the symptoms that can be contracted by a COVID-19 patient?
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- 19 Feb, 2024
- 1 location
The Effects of Natural Sugars in Breast Milk on Healthy Infant Growth and Development
This study will investigate the effects of breastfeeding and breastmilk composition on infant gut microbiome development as well as obesity and cognitive outcomes. Breast milk contains certain natural sugars that can promote the growth of 'good' bacteria in the intestines and reduce the growth of harmful bacteria. The purpose of …
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- 19 Feb, 2024
- 1 location