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Found 2,822 clinical trials

G Gregory J Czarnota, PhD, MD

Pilot Study to Evaluate Photoacoustic Imaging in Head and Neck Cancer

In this study, PA imaging will be used to examine the physiological and physical changes in lymph node involvements of head and neck cancer during radiotherapy with or without chemotherapy. Our objective in this pilot study will be to evaluate if PA parameters change within the lymph node involvements during …

100 years and younger All Phase N/A
R Ruth Van der Looven, MD

Forced Lefthandedness in Neonatal Brachial Plexus Palsy (NBPP) Children

The aim of the project is to assess the neurophysiological and functional consequences of forced lefthandedness in a population with right neonatal brachial plexus palsy (NBPP).

6-23 years All Phase N/A
H Hongwei Li, M.D

The Impact of Frailty on Thrombosis of Elderly Patients With NVAF FTE-NVAF

This study aims to investigate the use of anticoagulants in elderly patients with non-valvular atrial fibrillation (NVAF) and the incidence of frailty in elderly patients with NVAF. After two years follow-up, we observe the incidence of thrombotic events and the influence of frailty on thrombotic events in elderly patients with …

65 years and older All Phase N/A
P Prithvi Patil, MS

Prospective Evaluation of Performance of Disposable Elevator Cap Duodenoscope During ERCP in Clinical Practice

Purpose: To evaluate overall performance of disposable TIP duodenoscopes and get insight from end-users regarding its performance during various steps of ERCP procedure as well as ease and feasibility of pre-procedure duodenoscope set up and post procedure manual cleaning as well as reprocessing. Research design: This is a prospective observational …

18 years and older All Phase N/A
T Tak Yeung LEUNG

Capturing Early Events in Human Parturition

This is a prospective observational study on normal singleton pregnant women who have no sign of labor at 40 weeks of gestation or pregnant women who admitted to hospital for any sign of labor at term, aiming to identify labor-associated markers.

18 years and older Female Phase N/A
R Ruth E von Brachel, PHD

Reliability and Validity of the DIPS (Structured Interview) in a Community Sample

The DIPS (Diagnostisches Interview bei psychischen Strungen) is a structured interview to assess a variety of the most frequent psychological disorders. Its reliability and validity has been studied in clinical samples. Since structured interviews are also used in non-clinical samples like epidemiological research the investigators would like to conduct a …

18 years and older All Phase N/A
F For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR)

Attentional Performance in Parkinson Disease

Background Parkinson Disease (PD) is a nervous system disorder that affects movement. Dopamine is an important neurotransmitter in the brain. As PD progresses, there is less and less dopamine in the brain. Researchers think there may be a relationship between differences in attention and dopamine in people with PD. Objective …

35-80 years All Phase N/A
T Teresa Latham

Repeated Employee Testing for Understanding Our Recovery to Normal

The purpose of this research study is 1) to conduct a prospective longitudinal surveillance research trial, enrolling up to 200 CCHMC employees as they come back to work, and then following their clinical and laboratory parameters for up to 12 months; and 2) to support the ongoing development of diagnostic …

18 years and older All Phase N/A
J Juseok Ryu, PhD

Comparison of Somatometric Characteristics Between Cerebral Palsy and Normal Children Cross-sectional Multi Center Study

The purpose of this study is to: 1) secure basic data of patients with cerebral palsy, 2) seek ways to simplify the data for clinical application, 3) progress of hip dislocation, presence or absence of hip surgery, and The purpose of this study is to compare differences in body development …

1-13 years All Phase N/A
S Suria Loza Jalil, MD

Analysis of the Inflammatory Response and the Development of Humoral and Cellular Immunity in Patients With COVID-19

The SARS-CoV-2 infection in the airway epithelium induces cytopathic effects and the cessation of ciliary movement. Increased cytokines and chemokines have been reported to be associated with the severity of the disease. However, most of the molecular and cellular aspects of the inflammatory response and the processes of development of …

16 years and older All Phase N/A

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