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Found 486 clinical trials
Regulated Expiratory Breathing Method During Childbirth

The factors affecting the rate of primary caesarean section births are complex, and identifying interventions to reduce this rate is challenging. Effective interventions targeting at women are mainly represented by Childbirth training workshops, psychoeducation and psychosocial couple-based programs. Considering non medical interventions targeting mothers, the pattern of breathing during labor …

vaginal delivery
cesarean section
  • 0 views
  • 19 Feb, 2024
Post-surgical Liquid Biopsy-guided Treatment of Stage III and High-risk Stage II Colon Cancer Patients: the PEGASUS Trial

PEGASUS is a prospective multi-centric study designed to prove the feasibility of using liquid biopsy to guide the post-surgical and post-adjuvant clinical management in 140 microsatellite stable Stage-III and T4N0 Stage-II colon cancer patients.

colon cancer
stage ii colon cancer
folfiri regimen
cancer
ffpe
  • 0 views
  • 19 Feb, 2024
Balloon Lithoplasty for Preparation of Severely Calcified Coronary Lesions

Severely calcified coronary stenoses are difficult to treat with percutaneous coronary intervention (PCI) using current techniques and there is little specific evidence on how to best treat these cases. It is hypothesized that balloon lithoplasty is superior to conventional balloons for lesion preparation of severely calcified coronary lesions before stent …

percutaneous coronary intervention
antiplatelet therapy
exercise test
coronary artery stenosis
stenosis
  • 0 views
  • 19 Feb, 2024
Reinforced PTFE Meshes Versus Customized Titanium Meshes

The objective of this study is to compare two surgical techniques for the treatment of the maxillary and mandibular bone atrophies.. Therefore, the main purpose is to compare the (i) the percentage of post-operative complications (ii) the three-dimensional bone gain with customized titanium meshes (test group - the medical device …

partial edentulism
  • 0 views
  • 19 Feb, 2024
Shortened Antibiotic Treatment of 5 Days in Gram-negative Bacteremia

GNB5 is an investigator-initiated multicentre non-inferiority randomized controlled trial which aims to assess the efficacy and safety of shortened antibiotic for patients hospitalized with a Gram negative bacteremia with a urinary tract source of infection (GNB). Five days after initiation of antimicrobial therapy for GNB, participants are randomized 1:1 to …

  • 0 views
  • 19 Feb, 2024
Irreversible Electroporation of Unresectable Liver Tumors

The aim of this study is to evaluate the safety and feasibility of curative intended irreversible electroporation (IRE) in the treatment of liver tumors neighboring major vessels or bile ducts.

hepatoma
irreversible electroporation
liver tumor
cancer
metastasis
  • 0 views
  • 19 Feb, 2024
Doxapram Therapy in Preterm Infants (DOXA Trial)

Preterm infants often suffer from apnea of prematurity (AOP; a cessation of breathing) due to immaturity of the respiratory system. AOP can lead to oxygen shortage and a low heart rate which might harm the development of the newborn, especially the central nervous system. In order to prevent oxygen shortage, …

pulmonary disease
nervous
mechanical ventilation
continuous positive airway pressure
off-label
  • 0 views
  • 19 Feb, 2024
Short Structured Psychological Intervention for Adults With ADHD - a Randomized Controlled Trial

The purpose of this study is to evaluate the effects of a novel psychological intervention for adult ADHD through a randomized controlled trial. Participants will be randomized to receive either a face-to-face manualized short psychological intervention, SAINT, or corresponding self-help material with limited access to therapist support. The main objective …

attention deficit hyperactivity disorder
stimulant
psychiatric symptoms
substance use
cns stimulants
  • 0 views
  • 19 Feb, 2024
The Intensive Post Exclusive Enteral Nutrition Study

Crohn's disease (CD) is a chronic inflammatory condition with phases where the disease is active and other, where there are no symptoms. Exclusive enteral nutrition (EEN), a liquid only diet without allowance of any extra food, is the main treatment for children with active CD. However, when children stop the …

crohn's disease
tube feeding
enteral nutrition
  • 0 views
  • 19 Feb, 2024
Pilot Study to Evaluate the Effect of Nicotinamide Riboside on Immune Activation in Psoriasis

Background Psoriasis causes chronic inflammation in the body. Researchers want to see if a kind of vitamin B3 dietary supplement can help. This might lead to more treatment options. Objective To test if the dietary supplement nicotinamide riboside can improve immune system function in the blood and skin of people …

chronic inflammation
psoriasis
niacin
nicotinamide
vitamins
  • 0 views
  • 19 Feb, 2024