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Found 249 clinical trials
SAR408701 Versus Docetaxel in Previously Treated Carcinoembryonic Antigen-related Cell Adhesion Molecule 5 (CEACAM5) Positive Metastatic Non-squamous Non-small Cell Lung Cancer Patients

Primary Objectives: Study is designed with two primary endpoints that will be analyzed on randomized participants at the time of the cutoff date for each given analysis (progressive free survival [PFS] and overall survival [OS]). Study success is defined either on PFS or OS The primary objective is to determine …

measurable disease
non-small cell lung cancer
metastasis
cancer
immune checkpoint inhibitor
  • 0 views
  • 19 Feb, 2024
  • 169 locations
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer ALCHEMIST Chemo-IO Study

The purpose of this trial is to find out if the addition of pembrolizumab to usual chemotherapy is better or worse than usual chemotherapy alone for non-small cell lung cancer.

immunohistochemistry
stage iiia lung cancer ajcc v7
sarcoma
immunodeficiency
kaposi sarcoma
  • 0 views
  • 19 Feb, 2024
  • 359 locations
cfDNA Methylation Assay for Clinical Evaluation of Patients With Stage IA Lung Cancer After Ablation Operation

The objective is to screen and monitor the efficacy of cfDNA methylation in patients with stage I lung cancer after ablation, to compare the similarities and differences of cfDNA methylation between surgical treatment and ablation in patients with stage I lung cancer, and to look for new indicators to assess …

cancer
ct scan chest
chest ct
lung cancer
cfdna
  • 0 views
  • 19 Feb, 2024
  • 1 location
ELUCIDATE: Enabling LUng Cancer IDentification Using folATE Receptor Targeting

This is a phase 3, multi-center, single dose, open-label, exploratory study in suspected lung cancer patients scheduled to undergo endoscopic or thoracic surgery per CT/PET/MRI or other imaging based on standard of care. This study aims to assess the efficacy of OTL38 and Near Infrared Imaging (NIR) at identifying pulmonary …

thoracoscopy
infrared imaging
cancer
folic acid
lung cancer
  • 0 views
  • 19 Feb, 2024
  • 5 locations
Pembrolizumab Plus Pemetrexed for Elderly Patients With Non-Sq NSCLC With PD-L1 < 50%: CJLSG1901

To evaluate the efficacy and safety of Pembrolizumab + Pemetrexed in elderly patients with non-squamous non-small cell lung cancer with Programmed cell death (PD) -ligand1 (L1) tumor proportion score (TPS) of less than 50%.

measurable disease
pembrolizumab
adjuvant therapy
squamous non-small cell lung carcinoma
pemetrexed
  • 0 views
  • 19 Feb, 2024
  • 1 location
A Study With Pembrolizumab for Non-small Cell Lung Cancer (NSCLC)

This study is a randomized, national multicenter clinical study which is designed to compare the efficacy of the safety and efficacy of treatment every 3 weeks or 6 weeks in (Non-small-cell-cell cancer, NSCLC) subjects without systematic treatment who used Pembrolizumab after 6 cycles of combined chemotherapy estimated with stable efficacy …

  • 0 views
  • 19 Feb, 2024
  • 1 location
Black Raspberry Nectar for the Prevention of Lung Cancer BE WELL Study

This trial studies how well black raspberry nectar works in changing the gut microbiome and in reducing inflammatory processes that may lead to lung cancer. Studying the effects of black raspberry beverage on inflammation may help doctors find strategies to reduce the risk of developing lung cancer.

vitamins
cancer
lung carcinoma
carcinoma
lung cancer
  • 0 views
  • 19 Feb, 2024
  • 1 location
Lung Surgery With Enhanced Recovery VS. Lung Surgery Without Enhanced Recovery

This study aimed to determine the impact of an Enhanced Recovery Surgery pathway on short- term and long- term results in patients undergoing lung resection for primary lung cancer. Methods: A Randomized Controlled Trial was designed to collect the perioperative data on consecutive patients undergoing lung resection for primary lung …

lung surgery
cancer
enhanced recovery after surgery
pulmonary resection
lung cancer
  • 18 views
  • 19 Feb, 2024
  • 1 location
Self-Management Survivorship Care in Stage I-III Non-small Cell Lung Cancer or Colorectal Cancer

Participating in the program may improve knowledge and confidence about follow-up care, communication with cancer care and primary care doctors, and quality of life after cancer treatment in non-small cell lung cancer or colorectal cancer survivors.

stage iii lung cancer ajcc v8
stage iia lung cancer ajcc v8
stage ia3 lung cancer ajcc v8
stage iii colorectal cancer ajcc v8
stage iiib lung cancer ajcc v8
  • 4 views
  • 19 Feb, 2024
  • 1 location
A Safety Study of Oral Venetoclax in Combination With Intravenous Pembrolizumab in Adult Participants With Previously Untreated Non-Small Cell Lung Cancer (NSCLC) With High Programmed Cell Death Ligand-1 (PD-L1) Expression

Non-Small Cell Lung Cancer (NSCLC) is a solid tumor, a disease in which cancer cells form in the tissues of the lung. It is the most common form of lung cancer, accounting for around 85% of lung cancers.

measurable disease
epidermal growth factor
lymphoma
pembrolizumab
growth factor
  • 0 views
  • 19 Feb, 2024
  • 39 locations