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Found 18 clinical trials
Scandinavian Diverticulitis Trial SCANDIV-II

This study focuses on the treatment for complicated diverticulitis classified as Hinchey I-IV. The aim of this prospective observational study is to evaluate type of treatment and the success rate of treatment in acute complicated diverticulitis (ACD) at participating hospitals in Sweden and Norway. Furthermore, the effects on quality of …

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  • 19 Feb, 2024
Intestinal Flora Research Plan for Critically Ill Patients

More and more critically ill patients have improved early survival, they have been suffering from organ damage and inflammation for a long time, which is called chronic critical illness (CCI). Among CCI, persistent inflammatory response-immunosuppression-catabolic syndrome (PICS) is a special type of chronic severe disease, and immune paralysis is its …

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  • 19 Feb, 2024
Predictors of Better Outcomes After Severe Acquired Brain Injuries

Severe Acquired Brain Injury is defined as a traumatic, post-anoxic, vascular or other brain damage that causes coma for at least 24 hours and leads to permanent disability with sensorial, motor, cognitive or compartmental impairment. In this context, an accurate characterization of individual patients' profile in terms of neuronal damage, …

bdnf
coma
perinatal brain injury
traumatic brain injury
genetic analysis
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  • 19 Feb, 2024
The Effect and Mechanism of lncRNA NBR2 Regulating Endothelial Pyroptosis by Targeting GSDMD in Sepsis

Endothelial pyroptosis is a vital mechanism of vascular endothelial injury in sepsis; mitigation or abolishment of endothelial cell pyroptosis alleviate vascular endothelial damage and improve the prognosis of sepsis mice.

long non-coding rna
dysregulated host response
septicemia
cell injury
organ failure
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  • 19 Feb, 2024
Interest of a Period of Fasting Before Extubation in Resuscitation Patients

Gastric motility in resuscitation patients may be impaired for many reasons: Iatrogenic: Catecholamines, sedatives and opioids slow down the digestive system and decrease the tone of the lower esophageal sphincter Shock, polytrauma, sepsis, pain or discomfort, or mechanical ventilation again create an alteration in gastric emptying. Enteral nutrition is commonly …

enteral nutrition
opioids
fasting
mechanical ventilation
antral
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  • 19 Feb, 2024
Cardiac Biomarkers in Preeclampsia: Prediction of Disease and the Risk of Future Cardiovascular Events in Survivors

SUMMARY Background: Improvements in the management and prevention of obstetric haemorrhage and sepsis, in addition to magnesium sulphate for preeclampsia have led to significant reduction in global maternal mortality rates; thus leaving increasing number of survivors of preeclampsia than previously.

myocardial infarction
apob
atherosclerosis
heart disease
hscrp
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  • 19 Feb, 2024
Microbiota in COVID-19 Patients for Future Therapeutic and Preventive Approaches

In light of the rapidly emerging pandemic of SARS-CoV-2 infections, the global population and health care systems are facing unprecedented challenges through the combination of transmission and the potential for severe disease. Acute respiratory distress syndrome (ARDS) has been found with unusual clinical features dominated by substantial alveolar fluid load. …

covid-19
lower respiratory tract infection
critical illness
acute respiratory syndrome (sars)
respiratory tract infection
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  • 19 Feb, 2024
Skin-to-skin Contact in Neonatal Intensive Care Unit (NICU) Caregiving Touch and Neural Correlates of Slow Stroking Touch in Preterm Infants

Preterm (PT) infants spend their first weeks of life in Neonatal Intensive Care Unit (NICU) where receive little affective physical contact, which plays a crucial role in brain development. Evidence indicates that skin-to-skin contact (SSC) has a positive effect on infants' neurophysiological and behavioral adjustment to postnatal life. Moreover, caregiving …

social interaction
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  • 19 Feb, 2024