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Found 17 clinical trials
An Observational Study on Sarilumab-exposed Pregnancies

Primary Objective: To evaluate the relative risk of major structural birth defects, specifically a pattern of anomalies, in sarilumab-exposed pregnancies compared to disease-matched unexposed pregnancies. Secondary Objective: To evaluate the risk for sarilumab-exposure relative to the group of healthy pregnant women, and the effect of exposure on other adverse pregnancy …

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  • 19 Feb, 2024
  • 2 locations
Determination of Diastolic Dysfunction by Single Lead Electrocardiogram

It is a prospective, controlled, single-center, non-randomized, observational study. From September 2019 to December 2020, the study plans to prospectively include 400 patients aged 18 to 90 years. Every patients will undergo an echocardiographic examination with assessment diastolic dysfunction of the left ventricle, and registration of an electrocardiogram using a …

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  • 19 Feb, 2024
The ATtune Knee Outcome Study

To accomodate dissatisfied patients with a total knee arthroplasty (TKA) and improve outcomes, several knee systems have been developed. The cemented ATTUNE TKA shows superiority over other established knee systems at short-term, abating with longer follow-up. There have been no studies reporting on the results of the uncemented version of …

osteoarthritis
total knee replacement
joint replacement
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  • 19 Feb, 2024
Study to Gather Information About the Use of Healthcare Services and the Way the Disease is Cared for in Canadian Patients With Prostate Gland Cancer Which Spread Throughout the Body

Study to gather information about the optimal placement of Ra-223 in the order of different treatments in terms of the effect on patients and in terms of the use of healthcare services for the treatment of Canadian patients with prostate gland cancer which spread to other parts of the body.

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  • 19 Feb, 2024
Rheumatology Patient Registry and Biorepository

To facilitate clinical, basic science, and translational research projects involving the study of rheumatic diseases.

skin disease
ankylosing spondylitis
scleroderma
polymyalgia rheumatica
arthritis
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  • 19 Feb, 2024
Impact of DNA Repair Pathway Alterations on Sensitivity to Radium-223 in Bone Metastatic Castration-resistant Prostate Cancer

This phase II study investigates how well radium-223 works in treating patients with castration-resistant prostate cancer than has spread to the bones (bone metastases). Prostate cancer is the most common cancer in men and the second leading cause of cancer death. Furthermore, many men with notably advanced disease have been …

metastatic castration-resistant prostate cancer
dna damage
castration-resistant prostate cancer
prostate-specific antigen
prostate carcinoma
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  • 19 Feb, 2024
Surface Landmarks and C-length as Predictors of Depth of Right IJV Catheter Insertion: A TEE-Guided Study

The primary aim of the current study is to examine the accuracy of the C-distance or surface landmarks in determining the length of central venous catheter (CVC) that is required to place the catheter tip at the mid-superior vena cava (SCV) as confirmed by transesophageal echocardiography (TEE). A secondary aim …

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  • 19 Feb, 2024