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Found 15 clinical trials
Dose Escalation of DF6002 in Patients With Advanced Solid Tumors and Expansion in Selected Indications

This study is a Phase 1/2, open-label, dose-escalation study with a consecutive parallel-group efficacy expansion study, designed to determine the safety, tolerability, PK, pharmacodynamics, and preliminary anti-tumor activity of DF6002 as monotherapy and in combination with pembrolizumab.

non-small cell lung cancer
advanced renal cell carcinoma
metastatic transitional cell carcinoma
immunomodulators
cancers, ovarian
  • 0 views
  • 19 Feb, 2024
  • 1 location
Carrimycin in Patients With Locally Advanced Recurrent or Metastatic HNSCC (Non NPC): A Phase I Trial

The trial is a study conducted to evaluate the safety, tolerability and PK characteristics of Carrimycin tablet and measure its anti-tumor efficacy initially in the treatment of patients with locally advanced, recurrent, or metastatic head and neck squamous cell carcinoma (non NPC).

metastatic head and neck squamous cell carcinoma
squamous cell carcinoma of head and neck
metastatic head and neck squamous cell cancer
platelet count
aptt
  • 0 views
  • 19 Feb, 2024
  • 1 location
Concurrent Chemoradiotherapy With Nimotuzumab for High Risk Nasopharyngeal Carcinoma

This is the first phase II randomized clinical trial of concurrent chemoradiotherapy with or without EGFR blocker Nimotuzumab for high risk advanced nasopharyngeal carcinoma(NPC) , determining whether concurrent chemoradiotherapy(CCRT) combined with nimotuzumab can improve the survival rate of high-risk patients and may provide new evidence for individualized comprehensive treatment of …

chemoradiotherapy
epstein-barr virus dna
nasopharyngeal carcinoma
egfr blocker
nimotuzumab
  • 4 views
  • 19 Feb, 2024
  • 1 location
Radiotherapy Plus Nimotuzumab or Cisplatin in Nasopharyngeal Carcinoma

This is a phase III randomized clinical trial of definitive radiotherapy plus EGFR blocker nimotuzumab versus radiotherapy plus cisplatin(CCRT) for nasopharyngeal carcinoma (NPC) patients with favorable response to induction chemotheray(IC), determining whether radiotherapy combined with nimotuzumab was non-inferior to CCRT and may provide new evidence for individualized comprehensive treatment of …

epstein-barr virus dna
nasopharyngeal carcinoma
egfr blocker
nimotuzumab
induction chemotherapy
  • 0 views
  • 19 Feb, 2024
  • 1 location
Bioequivalence and the Tolerability and Antitumor Activity of Selinexor Combination Treatment

This is a Phase 1, two-part, two-arm, open-label study in patients with NSCLC who have had 1 or 2 prior lines of treatment, with 1 line containing a CPI, or patients with CRC who have had 2 prior lines of treatment (oxaliplatin- and irinotecan-based) and no prior immunotherapy. The study …

non-small cell lung cancer
monoclonal antibody therapy
fluorouracil
carcinoma
leucovorin
  • 0 views
  • 19 Feb, 2024
  • 3 locations