Found 40 clinical trials
Lu AF28996 in Patients With Parkinson's Disease (PD)
The purpose of this study is to investigate the safety of Lu AF28996, how well it is tolerated and what the body does to the drug in Patients With Parkinson's Disease
- 0 views
- 19 Feb, 2024
- 1 location
Apomorphine Pump in Early Stage of Parkinson's Disease (EARLY-PUMP)
The aim of the study is to assess the use of the apomorphine pump in earlier stages of Parkinson' Disease (PD), when motor complications have just developed and before patients are significantly affected in their social and occupational functioning.
- 0 views
- 19 Feb, 2024
- 21 locations
Blood-Brain-Barrier Disruption With Cerezyme in Patient's With Parkinson's Disease
This clinical trial focus on the delivery of Cerezyme in Parkinson's Disease (PD) patients using MR-guided focused ultrasound (MRgFUS) induced opening of the blood-brain barrier (BBB).
- 16 views
- 19 Feb, 2024
- 1 location
Effects of Directional Subthalamic Deep Brain Stimulation on Gait and Balance in Parkinson's Disease Patients
Deep brain stimulation of the NST is effective for cardinal motor signs in patients with idiopathic Parkinson's disease (IPD), its effects on gait disturbances, especially freezing of gait-FOG, and falls are variable from one patient to another, in part depending on the location of the NST-stimulating contact.
- 0 views
- 19 Feb, 2024
- 1 location
Application of LLM Care and Related Affective Computing Systems on People With Parkinson's Disease
The study is an adaptation of the Long Lasting Memories (LLM) (NCT02267499) and the subsequent LLM Care (NCT02313935) projects in patients with Parkinson's Disease (PD). The study aims to examine the viability and any potential benefits of cognitive and physical training, as offered via the ICT-based (non-pharmacological) intervention of LLM …
- 0 views
- 19 Feb, 2024
- 1 location
Aquatic Group Exercise for People With Parkinson Disease
This study will investigate the impact of land based or aquatic based group exercise on the balance, walking, balance confidence, and quality of life of people with idiopathic Parkinson disease. Participants will be randomized to participate in a land based or aquatic based group exercise program 2 times per week …
- 0 views
- 19 Feb, 2024
- 1 location
Open-Label Study With Pimavanserin on Activities of Daily Living in Subjects With Parkinson's Disease Psychosis
To assess the effect of pimavanserin on the activities of daily living in subjects with Parkinson's Disease Psychosis
- 0 views
- 19 Feb, 2024
- 19 locations
Modulation of GABA-A Receptors in Parkinson Disease-Transdermal Flumazenil Arm
The arm of this study evaluates possible GABA-A receptor target engagement effects of the FDA-approved medication, transdermal flumazenil (added 4/2020, replaced clarithromycin), in the setting of Parkinson's disease. Half of the subjects will receive transdermal flumazenil for 7-10 days, and half will receive a placebo. [11C]Flumazenil GABA-A receptor PET imaging …
- 0 views
- 19 Feb, 2024
- 1 location
Multidisciplinary Study of Novel NMDA Modulation for Neurodegenerative Disorder
Alzheimer's disease (AD) and Parkinson's disease (PD) are currently the leading neurodegenerative disorders. Considering the fact that aged population is rapidly growing, it has become a critical issue to find more effective medications for these two disorders.
- 0 views
- 19 Feb, 2024
- 1 location
Effect of Ketone Esters in Parkinson's Disease
As Mitochondrial dysfunction is one of the proposed mechanism of neuronal injury in Parkinson's disease, the study aims to assess the tolerability,side effects and effect of oral ketone esters in Patients with Parkinson's disease.
- 0 views
- 19 Feb, 2024
- 1 location