Found 14 clinical trials
Selinexor (KPT-330) in Combination With Temozolomide and Radiation Therapy in Patients With Newly Diagnosed Glioblastoma
Objective To learn the highest dose of selinexor that people with brain cancer can tolerate when given with temozolomide and radiation therapy. Eligibility People ages 18 and older with brain cancer that has not been treated with chemotherapy or radiation Design Participants will be screened under another protocol.
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- 19 Feb, 2024
- 1 location
Restrictive Use of Dexamethasone in Glioblastoma
The administration of steroids, most commonly dexamethasone (DEX), has established as standard of care during treatment of glioblastoma (GBM) and is widely used during the entire course of the disease including pre- and postoperative management, chemo- and radiotherapy. The primary purpose is to reduce tumor-associated vasogenic edema and to prevent …
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- 19 Feb, 2024
- 1 location
Cerebral Morbidity After Radiation Therapy for Brain Tumors
All types of brain tumours apart from glioblastoma will be included.
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- 19 Feb, 2024
- 4 locations
Hyperlactatemia During and After Tumorcraniotomy
This study aims to investigate the association between hyperlactatemia and neurological disability, length-of-stay and mortality in patients who undergo tumorcraniotomy. The risk factors that induce lactat accumulation will also be explored.
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- 19 Feb, 2024
- 1 location
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