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Found 19 clinical trials
Tipifarnib for the Treatment of Advanced Solid Tumors Lymphoma or Histiocytic Disorders With HRAS Gene Alterations a Pediatric MATCH Treatment Trial

This phase II pediatric MATCH trial studies how well tipifarnib works in treating patients with solid tumors that have spread to other places in the body (advanced), lymphoma, or histiocytic disorders that have HRAS genetic alterations. Tipifarnib may block the growth of cancer cells that have specific genetic changes in …

glomerular filtration rate
recurrent melanoma
lymphoma
cns tumor
melanoma
  • 0 views
  • 19 Feb, 2024
Targeted Drug Combined With CHOP in the Treatment of Newly Diagnosed Peripheral T-cell Lymphoma

This prospectivemulti-centeropen-label, controlled study will evaluate the efficacy and safety of targeted drug in combination with CHOP in treatment of newly diagnosed peripheral T-cell lymphoma.

lymphoma
t-cell lymphoma
measurable disease
pet/ct scan
peripheral t-cell lymphoma
  • 0 views
  • 19 Feb, 2024
Azacitidine Combined With Chidamide in the Treatment of Newly Diagnosed PTCL Unfit for Conventional Chemotherapy

This prospective, open-label, single-arm study will evaluate the efficacy and safety of azacitidine in combination with chidamide in treatment of newly diagnosed peripheral T-cell lymphoma unfit for conventional chemotherapy.

chidamide
lymphoma
pet/ct scan
peripheral t-cell lymphoma
azacitidine
  • 0 views
  • 19 Feb, 2024
Anti-PD-1 Antibody Combined With Peg-Asparaginase and Chidamide for the Early Stage of NK/T Cell Lymphoma

This prospective pilot study to evaluate the efficacy and safety of the anti-PD-1 antibody combine with Peg-asparaginase and Chidamide regimen for stage IE and IIE ENKTL.

electrocardiogram
ct scan
renal function
peg-asparaginase
biological therapy
  • 0 views
  • 19 Feb, 2024
VR-CAP in the First-line Treatment for Patients With Marginal Zone Lymphoma

This is a prospective single arm, multi-center, phase II clinical trial to observe the efficacy and safety of VR-CAP (Velcade and Rituximab-Cyclophosphamide, Epirubicin and Prednisone) in the first-line treatment for patients with marginal zone lymphoma.

epirubicin
marginal zone lymphoma
lymphoma
malt
cyclophosphamide
  • 0 views
  • 19 Feb, 2024
Efficacy and Safety of Lenalidomide With or Without Rituximab and Other Drugs in B-cell Non-Hodgkin's Lymphomas

Describe the treatment of B-cell non-Hodgkin lymphoma patients who receive lenalidomide single drug or lenalidomide combined with rituximab (with or without other drugs), and evaluate the efficacy and safety of lenalidomide single drug or lenalidomide combined with rituximab (with or without other drugs) in the real-world setting.

hodgkin's disease
lenalidomide
lymphoma
rituximab
b-cell lymphoma
  • 0 views
  • 19 Feb, 2024
Multiple Myeloma and Environmental Exposure to Pesticides in the French West Indies: A Population Based Case-control Study.

Multiple myeloma (MM) is a malignancy of plasma cells engaging in monoclonal immunoglobulin production. A strong presumption was established between exposure to pesticides and the risk of MM. The French West Indies departments of Guadeloupe and Martinique are characterized by a wide use of pesticides related to bananas plantation, particularly …

multiple myeloma
monoclonal protein
cancer
monoclonal antibodies
immunoglobulins
  • 0 views
  • 19 Feb, 2024
A Single-cell Transcriptome Study in Patients With Non-Hodgkin's Lymphoma

Using single-cell RNA sequencing, this study will explore the heterogeneity of lymphoma inside and outside the lymph node, identify tumor specific molecular markers and cell subgroups, explore the differences in tumor microenvironment composition, and provide a basis for diagnosis and precision treatment.

hodgkin's disease
lymphoma
non-hodgkin lymphoma
  • 0 views
  • 19 Feb, 2024
Comparing Sensory Modulation Anxiety and Quality of Life Between Children With Primary Headaches and Healthy Peers

Study hypotheses: Children with headaches will show significantly higher sensory reactivity, higher anxiety level and lower quality of life that health controls. Among children with headaches, sensory reactivity will significantly correlate with higher anxiety level and lower quality of life. Among children with headaches quality of life will be predicted …

attention deficit hyperactivity disorder
chronic disease
pediatric
anxiety
headache
  • 0 views
  • 19 Feb, 2024