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Found 40 clinical trials
Heart Transplantation Using Normothermic Regional Perfusion Donation After Circulatory Death

Normothermic regional perfusion (NRP) utilizes Extracorporeal Membrane Oxygenation (ECMO) or cardiopulmonary bypass to reperfuse the heart and other organs in situ after isolation and ligation of the cerebral vessels. In situ resuscitation of the heart has the added advantage of allowing full hemodynamic and echocardiographic assessment of the donor heart …

heart transplantation
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  • 19 Feb, 2024
Ablation Versus Medical Management of Atrial Fibrillation in HFpEF

This is a prospective non-blinded randomized control pilot study comparing the effect of pulmonary vein isolation against medical management of atrial fibrillation in patients with Heart Failure with preserved Ejection Fraction (HFpEF).

hypertrophy
pulmonary vein isolation
holter monitor
pro-brain natriuretic peptide
left ventricular hypertrophy
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  • 19 Feb, 2024
Effect of Nutritional Supplementation and Pulmonary Rehabilitation on the Clinical Status of HF and COPD

Cardiovascular diseases (CVD) are the leading cause of death in the world and our country. The prevalence of Heart Failure (HF) is 1-2% in the adult population in developed countries, up to 10% among people 70 years of age. Concerning COPD, it is estimated that by 2030 will be the …

lung disorder
bronchodilator
pulmonary disease
leucine
pulmonary rehabilitation
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  • 19 Feb, 2024
CPAP on Acute Stroke and OSA

Traditionally, recurrence of cardiovascular or cerebrovascular events uses documented mortality, morbidity or hospitalization for heart failure, acute coronary syndrome or stroke as clinical endpoints. Recently, several studies showed that enlarged left atrium (LA) can serve as a predictor for recurrent stroke or cardiovascular events.

ct scan
sleep apnea
recurrent stroke
heart failure, acute
stroke
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  • 19 Feb, 2024
Myocardial Contrast Echocardiography in Septic Patients

Myocardial microcirculatory alterations may be involved in the pathogenesis of acute cardiac dysfunction or septic cardiomyopathy in septic patients. The investigators study the cardiac function (systolic and diastolic) with two-dimensional echocardiography (TTE), and the myocardial microcirculation with contrast echocardiography (MCE) and sulphur hexafluoride microbubbles Sonovue injection in ICU septic patients.

resuscitation
serum lactate
dysregulated host response
cardiomyopathy
vasoconstrictors
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  • 19 Feb, 2024
Assessment of Paravalvular Leak After TAVI by Hemodynamic Measurements and Cardiac MRI

Rationale: Transcatheter aortic valve implantation (TAVI) has become the standard therapy for elderly patients with high surgical risks. Paravalvular leakage after TAVI is relatively common and there is conflicting evidence regarding the clinical impact of mild paravalvular leakage in self-expanding devices. Prospective data for self-expanding devices are required to compare …

vascular complications
regurgitation
syncope
thoracic surgery
angiography
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  • 19 Feb, 2024
Invasive Coronary Angiography Early in Ischemic Heart Failure

To compare the outcomes of patients with acute heart failure who undergo early coronary angiography vs. usual care

myocardial infarction
angina pectoris
angiography
angina
acute heart failure
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  • 19 Feb, 2024
Prediction of Outcome by Echocardiography in Left Bundle Branch Block

Patients with left bundle branch block have an increased risk for the development of heart-failure and death. However, risk factors for unfavorable outcomes are still poorly defined. This study aims to identify echocardiographic parameters and ECG characteristics by machine learning in order to develop individual risk assessment

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  • 19 Feb, 2024
Prospective Register on the Etiologies of Cardiogenic Shock and Their Prognosis at One Year.

Cardiogenic shock (CC) is one of the major challenges of current cardiology. Despite the difficulty of establishing a strict and consensual definition, it is accepted that the CC clinically corresponds to persistent hypotension (systolic blood pressure 90 mmHg for at least 30 minutes or need for vasopressor support) associated with …

vasopressor
systolic blood pressure
hyperlactatemia
shock
pulmonary edema
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  • 19 Feb, 2024
Detection of Heart Conditions With Single Lead ECG Using Artificial Intelligence

The purpose of this research is to prospectively test and validate the single-lead Low EF algorithm in outpatients in order to test the performance of a single-lead ECG based algorithm to identify people with decreased left ventricular EF.

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  • 19 Feb, 2024