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Found 12 clinical trials
Adenosine Receptor Antagonist Combination Therapy for Metastatic Castrate Resistant Prostate Cancer

This is a Phase 1b/2, open-label, multicenter platform trial to evaluate the antitumor activity and safety of AB928-based combination therapy in participants with metastatic castrate resistant prostate cancer (mCRPC).

measurable disease
prostatic neoplasms, castration-resistant
antiandrogens
testosterone
cancer
  • 0 views
  • 19 Feb, 2024
Impact of DNA Repair Pathway Alterations on Sensitivity to Radium-223 in Bone Metastatic Castration-resistant Prostate Cancer

This phase II study investigates how well radium-223 works in treating patients with castration-resistant prostate cancer than has spread to the bones (bone metastases). Prostate cancer is the most common cancer in men and the second leading cause of cancer death.

bone metastases
carcinoma
stage iv prostate cancer
castration-resistant prostate cancer
biospecimen collection
  • 0 views
  • 19 Feb, 2024