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Found 104 clinical trials
Phase 2 Study of SAR439859 Versus Physician's Choice in Locally Advanced or Metastatic ER-positive Breast Cancer (AMEERA-3)

Primary Objective: To determine whether SAR439859 per os improves progression free survival (PFS) when compared with a endocrine monotherapy of the choice of the physician, in participants with metastatic or locally advanced breast cancer. Secondary Objectives: To compare the overall survival in the 2 treatment arms To assess the objective …

HER2
stage iv breast cancer
cancer metastatic
fulvestrant
estrogen receptor-positive breast cancer
  • 0 views
  • 19 Feb, 2024
  • 126 locations
Transcutaneous Breast Cancer Diagnosis by Canine Odorology

Patient with an indication of interventional percutaneous procedure for characterization of a breast lesion, palpable or not, classified as category 4 or 5, according to the Breast Imaging (BI) Report and Data System of the American College of Radiology (RADS) classification detected at mammography and/or breast ultrasound examination.

insulin
breast carcinoma
fever
ultrasound breast
breast imaging reporting and data system
  • 0 views
  • 19 Feb, 2024
SBRT for Breast Cancer Oligometastases

This is a prospective data collection of treatment outcome for newly diagnosed oligometastatic breast cancers with 1-3 bone metastases. Eligible patients will be identified from the weekly Breast MDC. Patients will receive the recommended systemic and local treatment (including metastases directed SBRT) according to our clinical practice guidelines.Patients will be …

solid tumor
breast neoplasm malignant female
sbrt
breast cancer
metastasis
  • 0 views
  • 19 Feb, 2024
BREast Cancer And Sexuality Treatment

Groups will consist of approximately 8 breast cancer survivors and will be led by 2 trained therapists. Participants will complete four assessments (involving a clinician administered interview and standardized questions): pre-treatment, post- treatment, and 6 month follow up.

breast cancer
pain in breast
cancer
  • 0 views
  • 19 Feb, 2024
Liquid Biopsies and Imaging in Breast Cancer

The aim of the study is to show proof of concept for combining multi-parametric MRI with liquid biopsies in addition to conventional clinical and pathologic information, to accurately predict response to neoadjuvant treatment for patients with primary breast cancer.

breast carcinoma
trastuzumab
carcinoma
adjuvant therapy
pertuzumab
  • 0 views
  • 19 Feb, 2024
Genetic Characteristics of Metastatic Breast Cancer Patients

Genomic analysis for metastatic breast cancer(MBC) patients Participant (Inclusion criteria) Patients who diagnosed metastatic/stage IV breast cancer Patients who were not received treatment for metastatic breast cancer on palliative setting Process (1) Tissue/ Blood sample At diagnosis, MBC tissue / blood sample (20cc) will be obtained.

breast cancer
stage iv breast cancer
cancer
  • 0 views
  • 19 Feb, 2024
Multi-4SCAR-T Therapy Targeting Breast Cancer

The purpose of this study is to assess the feasibility, safety and efficacy of multiple 4th generation CAR-T cells targeting Her2, GD2, and CD44v6 surface antigen in breast cancer. Another goal of the study is to learn more about the activities of the multi-CAR T cells and their persistency in …

immunosuppressive agents
serum bilirubin
neutrophil count
immunosuppression
  • 2 views
  • 19 Feb, 2024
89Zr-atezolizumab PET Scan and Lobular Breast Cancer

The exploratory single center feasibility ImaGelato study is conducted as an imaging side study to the Dutch GELATO trial (Assessing efficacy of carboplatin and atezolizumab in metastatic lobular breast cancer). Ten patients with lobular metastatic breast cancer, who are included in the GELATO trial at the UMCG, are eligible for …

  • 0 views
  • 19 Feb, 2024
CIMER: Combined Immunotherapies in Metastatic ER+ Breast Cancer

Women with Hormone Receptor (HR)+ Human Epidermal growth factor Receptor (HER)2- metastatic breast cancer are eligible to a randomized trial. Patients receiving standard first line therapy for metastatic HR+ Breast cancer(BC) (letrozole+palbociclib) are randomly assigned to also receive Stereotactic Body Radiation Therapy(SBRT) to each metastatic lesion.

HER2
stage iv breast cancer
direct bilirubin
epidermal growth factor
oophorectomy
  • 0 views
  • 19 Feb, 2024
Exercise and Tumor Blood Flow in Breast Cancer Patients

This research aims at investigating tumor blood flow response to acute exercise in human cancer patients. It is hypothesized and expected that acute exercise increases tumor blood flow, which could plausibly increase the efficacy of cancer treatment.

cancer treatment
  • 0 views
  • 19 Feb, 2024