Found 21 clinical trials
COVID-19 Staff Testing of Antibody Responses Study (Co-Stars)
This study will perform prospective repeated serological antibody testing on a cohort of at least 1000 healthcare workers at Great Ormond Street Hospital. Within this cohort, a subset of 150-250 staff members with confirmed (PCR positive) SARS-CoV-2 disease will be followed with intensive monthly testing for 6 months to determine …
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- 19 Feb, 2024
Change in the Ratio of Mean Platelet Volume (MPV) to Platellet(PLT) in Covid-19 Pneumonia Patients
Previous studies claims that the proportion of mean platellet volume to platellet which can simply be determined with simple blood tests that are performed at admission, might predict the mortality in ARDS patients. Covid-19 pneumonia has a very similar clinical outlook with ARDS.
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- 19 Feb, 2024
Blood Biomarker of Alzheimer's Disease (AD)
In this study, we are testing a blood biomarker for stratification of Alzheimer's disease patients and healthy volunteers. This study may lead to future blood tests that may help earlier diagnosis of Alzheimer's disease and detect the disease progression.
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- 19 Feb, 2024
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Prospective Natural History Study of Smoking Immune Cell Profiles Epigenetics and COVID-19
Participants will have a final visit. They will have blood tests. If at any time participants test positive for a COVID-19, they will be rescheduled 14 days or more after they no longer have symptoms....
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- 19 Feb, 2024
The Malaria Heart Disease Study
The overall hypothesis is that patients who have (i) previously suffered from a malaria infection or (ii) patients with ongoing symptomatic malaria will benefit from having an echocardiogram and blood tests performed as a screening tool to diagnose early cardiac impairment and prevent future cardiovascular disease.
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- 19 Feb, 2024
Biomarkers of CASH
The project aims to develop prognostic and diagnostic blood tests for symptomatic brain hemorrhage in patients diagnosed with cavernous angiomas, a critical clinical challenge in a disease affecting more than a million Americans.
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- 19 Feb, 2024
Serial Tumour Biopsies and Blood Biomarkers in Melanoma
It is hoped that soon we will be able to monitor cancer by analysing a patient's blood samples, thus reducing the need for biopsies. As blood tests could be taken more frequently, signs that patients are becoming resistant to treatments could be picked up sooner. As well as monitoring biomarkers, …
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- 19 Feb, 2024
Natural History Study of Children and Adults With Adrenocortical Cancer (ACC)
For the scans, they will lie in a machine that takes pictures of the body. They may have blood tests. They may have a 24-hour urine collection. They may be asked to sign a new consent form for some of these tests. Participants will complete paper or electronic surveys.
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- 19 Feb, 2024
Clinical Manifestations and Biomarkers in Amyotrophic Lateral Sclerosis Type 4 and Other Inherited Neurological Disorders of RNA Processing
At visits, participants will undergo some or all of the following: Medical history Physical exam Tests of muscle strength and volume and physical function Blood tests Pregnancy test (for some females) Skin biopsy of forearm Magnetic resonance imaging (MRI) Dual x-ray absorptiometry (DEXA).
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- 19 Feb, 2024
Natural History Study of Children and Adults With Neuroendocrine Neoplasms (NEN)s
Participants medical records, test results, and imaging results will be reviewed. They may have scans and blood tests. They may sign a separate consent form for some of the tests. Participants will complete paper or electronic surveys.
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- 19 Feb, 2024