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Found 15 clinical trials
Evaluation of a TDM Program for Intensive Care Patients in the Cerebrospinal Fluid

However, the amount of antibiotics in the cerebrospinal fluid (CSF) in patients with ventriculitis or meningitis is still unclear. This study is a prospective study to evaluate the concentration of different antibiotics in the CSF in patients with an external ventricular drainage compared to antibiotic blood concentration.

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  • 19 Feb, 2024
Intestinal Flora Research Plan for Critically Ill Patients

Especially for acute stress, severe stress, the use of broad-spectrum antibiotics, vasoconstrictors and opioids, intestinal ischemia/reperfusion injury, epithelial cell apoptosis, barrier integrity destruction, gastrointestinal Changes in the motility of the tract, lack of nutrients in the intestinal cavity, etc.

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  • 19 Feb, 2024
Construct Validation of the BIOTICA Questionnaire

Based on barriers identified in a systematic literature search, a self-report questionnaire called "BIOTICA" has been developed by the research team to assess medication adherence barriers to oral AB. The purpose of the BIOTICA-questionnaire is to detect individual barriers that prevent the optimal intake of oral AB and thus, lead …

antibiotics
antibiotic therapy
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  • 19 Feb, 2024
Scandinavian Diverticulitis Trial SCANDIV-II

This study focuses on the treatment for complicated diverticulitis classified as Hinchey I-IV. The aim of this prospective observational study is to evaluate type of treatment and the success rate of treatment in acute complicated diverticulitis (ACD) at participating hospitals in Sweden and Norway. Furthermore, the effects on quality of …

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  • 19 Feb, 2024
Antibiotic Dosing in Geriatric Patients at the Emergency Department

In this pilot study, we will investigate whether - with the current dosing regimens, used in the Ghent University Hospital - pharmacodynamic targets regarding beta-lactam antibiotics (more specific Amoxicilline-Clavulanate, Piperacillin-Tazobactam and Temocillin) are attained in frail patients admitted to the geriatric department.

antibiotic therapy
beta-lactam
antibiotics
temocillin
hemoculture
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  • 19 Feb, 2024