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Found 187 clinical trials
Optimal EGFR TKIs Treatment Strategies for Lung Adenocarcinoma Harboring EGFR Exon 19 Deletion Variants

To determine the optimal EGFR TKIs treatment strategies for lung adenocarcinoma harboring EGFR exon 19 deletion variants

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  • 19 Feb, 2024
AML/MDS Drug Sensitization by in Vivo Chemotherapy Administration

In this study, the investigators will explore the feasibility of ex vivo drug screening to predict sensitivity to chemotherapy resistance and to identify novel synergy between chemotherapies.

midostaurin
gemtuzumab
leukemia
aml
myelodysplastic syndromes
  • 0 views
  • 19 Feb, 2024
Glucose Monitoring During Chemotherapy

Each patch lasts for about 2-weeks. During chemotherapy visits, new patches will be placed and will be worn until the chemotherapy course is complete. Participants will be in this study for 6 months.

adjuvant
cancer
breast cancer
immunostimulant
immunomodulators
  • 0 views
  • 19 Feb, 2024
Neoadjuvant Chemotherapy in Borderline Resectable and Locally Advanced Pancreatic Cancer

This is a Norwegian prospective observational study that evaluates the resectability rate in patients with borderline resectable and locally advanced pancreatic cancer who received neoadjuvant chemotherapy in a population based cohort. Eligible patients are treated with neoadjuvant chemotherapy possibly followed by surgical exploration and resection.

pancreatic adenocarcinoma
cancer
pancreatic cancer
surgical exploration
folfirinox
  • 0 views
  • 19 Feb, 2024
A Longitudinal Observational Biomarker Study in Pancreatic Cancer Patients Receiving Chemotherapy

Based on the literature, the pancreatic cancer treatment predictor biomarker, which is used in the domestic clinical field, is actually applied to the pancreatic cancer patient cohort of the National Cancer Center. To systematically prospectively identify prospective treatment response biomarkers for Pancreatic Cancer Cohort in the National Cancer Center

cancer treatment
cancer
  • 0 views
  • 19 Feb, 2024
Cancer Therapy Effects on the Heart

Anthracycline chemotherapies (e.g. doxorubicin, daunorubicin) is commonly given to treat pediatric cancer, and carries a risk of cardiotoxicity. Over the long term, children who receive these therapies have an increased risk of heart failure and early cardiovascular death.

cardiotoxicity
cancer treatment
cancer therapy
doxorubicin
daunorubicin
  • 0 views
  • 19 Feb, 2024
Evaluation of Antibody Response to High-Dose Seasonal Influenza Vaccination in Patients With Myeloid Malignancy Receiving Chemotherapy and Healthy Volunteers

This pilot research trial studies the antibody response to high-dose seasonal influenza vaccination in patients with myeloid malignancy receiving chemotherapy and healthy volunteers. Evaluating antibody response to high-dose seasonal influenza vaccine may serve as a basis for vaccine recommendations in patients with myeloid malignancies and provide insights into the status …

myeloid malignancy
antibody test
vaccination
antibody response
influenza vaccination
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  • 19 Feb, 2024
Validity and Reliability of the Turkish Version of the Head and Neck Cancer Inventory

Morbidities resulting from the combined application of radiotherapy and chemotherapy are based on more anecdotal information and critical data on long-term functional outcomes in this patient group are scarce.

head and neck cancer
neck cancer
cancer
  • 0 views
  • 19 Feb, 2024
The Real World Study of Neoadjuvant Immunotherapy in Early Stage NSCLC in China

Here we conducted this real world study to see whether neoadjuvant immunotherapy would bring MPR and survival benefits in NSCLC, for example, single agent immunotherapy or immunotherapy combination with chemotherapy. Furthermore biomarker analysis would be also performed to achieve personalized neoadjuvant immunotherapy.

non-small cell lung cancer
EGFR
small cell lung cancer
pneumonectomy
lung cancer
  • 0 views
  • 19 Feb, 2024
ABCB1/P-glycoprotein Expression Influence on Non-metastatic Osteosarcoma of the Extremities

After surgical treatment, the histological response to neoadjuvant chemotherapy will be evaluated. The histological response to primary chemotherapy will be expressed as a percentage of tumor necrosis. In the case of tumor necrosis above 90% the patient is defined as a "good responder" in case of a lower percentage as …

adriamycin
glycoprotein
adjuvant therapy
ejection fraction
tumor necrosis
  • 0 views
  • 19 Feb, 2024