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Found 178 clinical trials
Tipifarnib for the Treatment of Advanced Solid Tumors Lymphoma or Histiocytic Disorders With HRAS Gene Alterations a Pediatric MATCH Treatment Trial

This phase II pediatric MATCH trial studies how well tipifarnib works in treating patients with solid tumors that have spread to other places in the body (advanced), lymphoma, or histiocytic disorders that have HRAS genetic alterations. Tipifarnib may block the growth of cancer cells that have specific genetic changes in …

recurrent melanoma
recurrent osteosarcoma
refractory ependymoma
antineoplastic
recurrent thyroid gland carcinoma
  • 0 views
  • 19 Feb, 2024
  • 83 locations
Niraparib/TTFields in GBM

Evaluating the efficacy and safety of niraparib and Tumor-Treating Fields (TTFields) in recurrent glioblastoma (GBM).

renal function test
glioblastoma
karnofsky performance status
niraparib
tumor treating fields therapy
  • 0 views
  • 19 Feb, 2024
  • 1 location
Prediction of Therapeutic Response of Apatinib in Recurrent Gliomas

This study aims to collect clinical, radiological and histopathology imaging including detailed radiological data, survival data, clinical parameters, molecular pathology and images of HE slices in patients with recurrent gliomas whose are treated with Apatinib, for evaluating the efficacy and safety of Apatinib. Moreover, by leveraging artificial intelligence, this study …

tyrosine
glioma
apatinib
platelet count
liver metastasis
  • 0 views
  • 19 Feb, 2024
  • 1 location
MR Based Survival Prediction of Glioma Patients Using Artificial Intelligence

This registry aims to collect clinical, molecular and radiologic data including detailed survival data, clinical parameters, molecular pathology (1p/19q codeletion, MGMT methylation, IDH and TERTp mutations, etc) and conventional/advanced/new MR sequences (T1, T1c, T2, FLAIR, ADC, DTI, PWI, etc) of patients with primary gliomas. By leveraging artificial intelligence, this registry …

glioma
tumour resection
molecular pathology
flair
tumor resection
  • 0 views
  • 19 Feb, 2024
  • 1 location
Histopathology Images Based Survival Prediction of Glioma Patients Using Artificial Intelligence

This registry aims to collect clinical, molecular and histopathology imaging including detailed survival data, clinical parameters, molecular pathology (1p/19q codeletion, MGMT methylation, IDH and TERTp mutations, etc) and images of HE slices in primary gliomas. By leveraging artificial intelligence, this registry will seek to construct and refine hstopathology imaging based …

glioma
molecular pathology
tumor resection
tumour resection
  • 0 views
  • 19 Feb, 2024
  • 1 location
MR Based Prediction of Molecular Pathology in Glioma Using Artificial Intelligence

This registry aims to collect clinical, molecular and radiologic data including detailed clinical parameters, molecular pathology (1p/19q co-deletion, MGMT methylation, IDH and TERTp mutations, etc) and conventional/advanced/new MR sequences (T1, T1c, T2, FLAIR, ADC, DTI, PWI, etc) of patients with primary gliomas. By leveraging artificial intelligence, this registry will seek …

glioma
tumour resection
molecular pathology
flair
tumor resection
  • 0 views
  • 19 Feb, 2024
  • 1 location
Histopathology Images Based Prediction of Molecular Pathology in Glioma Using Artificial Intelligence

This registry aims to collect clinical, molecular and radiologic data including detailed clinical parameters, molecular pathology (1p/19q co-deletion, MGMT methylation, IDH and TERTp mutations, etc) and images of HE slices in primary gliomas. By leveraging artificial intelligence, this registry will seek to construct and refine histopathology image based algorithms that …

glioma
molecular pathology
tumor resection
tumour resection
  • 0 views
  • 19 Feb, 2024
  • 1 location
Survival Significance of Molecular Pathology and Genetic Variation in Brain Gliomas

This study seeks to find the prognostic and clinical significance based on molecular and genetic biomarkers/subgroups of gliomas.

glioma
tumour resection
molecular pathology
intracranial glioma
tumor resection
  • 0 views
  • 19 Feb, 2024
  • 1 location