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Found 997 clinical trials
To Evaluate the Safety Tolerability and Pharmacokinetics Profiles of TG-1000 in Healthy Volunteers and the Food Effect on Pharmacokinetics of Single Oral Dose of TG-1000 in Healthy Volunteers.

The purpose of this study is to evaluate the safety, tolerability, and pharmacokinetics profiles of TG-1000 in healthy volunteers, and to evaluate the food effect on pharmacokinetics of single oral dose of TG-1000 in healthy volunteers.

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  • 19 Feb, 2024
Safety and Efficacy Evaluation of ET-01 Transplantation in Subjects With Transfusion Dependent -Thalassaemia

This is an open label, single site study to evaluate the safety and Efficacy of ET-01 Transplantation in subjects with Transfusion Dependent -Thalassaemia.

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  • 19 Feb, 2024
UAB Alzheimer's Disease Center Core Cohort - Imaging Substudy

The primary objective of this study is to measure the concentration and the regional brain distribution of pathologic amyloid deposition using the PET tracer [C-11]PiB in participants in the UAB Alzheimer's Disease Center cohort. Assessment of interactions between race and vascular risk factors, brain amyloid levels measured with [C-11]PiB-PET, and …

alzheimer's disease
amyloid
amyloidosis
  • 0 views
  • 19 Feb, 2024
  • 1 location
Metformin for Abdominal Aortic Aneurysm Growth Inhibition

A multi-centre population-based open-label randomized controlled trial with allocation concealment and blinded outcome assessment will examine if up to 2g metformin daily slows AAA growth in patients with small AAAs who do not have diabetes.

aortic aneurysm
aneurysm
diabetes
metformin
abdominal aortic aneurysm
  • 0 views
  • 19 Feb, 2024
Histopathologic Effect of Calcium Electroporation on Cancer in the Skin

In this phase II study we investigate the effect of calcium electroporation on cancer in the skin investigated by histopathology.

cancer
endocrine therapy
hormone therapy
calcium
metastasis
  • 0 views
  • 19 Feb, 2024
Hypofractionated Radiotherapy in Elderly Patients With Head & Neck Squamous Cell Carcinoma

The purpose of this research study is to investigate a shorter radiation treatment schedule for head and neck cancers in patients 70 years of age and older. Standard radiation treatment for head and neck patients normally requires that the patient travel to the hospital daily for 6-7 weeks to receive …

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  • 19 Feb, 2024
Open-Label Study With Pimavanserin on Activities of Daily Living in Subjects With Parkinson's Disease Psychosis

To assess the effect of pimavanserin on the activities of daily living in subjects with Parkinson's Disease Psychosis

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  • 19 Feb, 2024
MRI Assessing Clinical Usability of STrategically Acquired Gradient Echo on Human Participants

The study's purpose is to validate STAGE images and, when applicable, their equivalence to conventional MRI through an assessment by a trained certified neuroradiologist in a clinical setting. For STAGE images without conventional equivalent, the neuroradiologist will determine if their contrasts, intensities, and quality are sufficient and meet expectations for …

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  • 19 Feb, 2024
Pelvic Floor Magnetic Stimulation in Women With Idiopathic Overactive Bladder

In clinical practice, Bladder Traininhg (BT) and Magnetic stimulation (MS) are frequently used together in the treatment of women with idiopathic overactive bladder (OAB). Up to our knowledge, there is no study evaluating the combined effect of magnetic stimulation and bladder training in women with idiopathic OAB in the literature. …

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  • 19 Feb, 2024
Treatment With Investigational Convalescent Plasma and Measure Antibody Levels in Patients Hospitalized With COVID-19

This is an open label pilot study designed to provide access to treatment with investigational convalescent plasma and assess the relationship between NAb titers in the investigational convalescent plasma compared to changes in NAb levels in the recipient in hospitalized patients with COVID-19.

acute respiratory syndrome (sars)
respiratory symptom
covid-19
  • 0 views
  • 19 Feb, 2024