Found 1764 clinical trials
SBRT Dose Escalation for Reirradiation of Inoperable Lung Lesions
Prospective phase I study to evaluate the maximum tolerated dose (MTD) of SBRT for thoracic re-irradiation. Dose limiting toxicity will be pneumonitis G3. The potential advantage of the dose escalation planned in this study is the delivery of an ablative dose to radically treat patients with inoperable local relapse, without …
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- 19 Feb, 2024
- 1 location
Connexin Genotypes in Cystic Fibrosis
Gap junction proteins might be of importance for the influx of blood cells into the lung and may influence the course of pulmonary inflammation. Aims: To assess the relationship between gap junction proteins alpha 1 (GJA1/Connexin 43) and alpha 4 (GJA4/connexin 37) genotypes and clinical disease phenotype.
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- 19 Feb, 2024
- 3 locations
A Study of COVID 19 Convalescent Plasma in High Risk Patients With COVID 19 Infection
Purpose of Study The purpose of this study to evaluate, the effectiveness of convalescent plasma in combatting the symptoms and effects of the coronavirus disease, COVID-19. Beyond supportive care, there are no proven treatment options for COVID-19.
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- 19 Feb, 2024
- 2 locations
Prone Positioning for Patients on General Medical Wards With COVID19
COVID-PRONE is a multicenter, pragmatic, single-blind, 2-arm, parallel, randomized controlled trial seeking to compare the pre-emptive prone positioning (i.e. encouraging patients to adopt a prone position before they require mechanical ventilation) to the control arm of standard care alone. Randomization will be stratified by site.
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- 19 Feb, 2024
- 7 locations
Study for Novel Coronavirus Pneumonia (NCP)
To develop practical and effective clinical diagnosis and treatment schemes for the control of novel coronavirus pneumonia.
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- 19 Feb, 2024
- 1 location
Understanding Immunity to SARS-CoV-2 the Coronavirus Causing COVID-19
The purpose of this study is to test over time immunity to SARS-CoV-2, a recently identified coronavirus responsible for the 2019 world-wide pneumonia outbreak known as COVID-19. Adults and children diagnosed with COVID-19 as well as controls without COVID-19 will be invited to participate in this study.
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- 19 Feb, 2024
- 1 location
Prediction of Clinical Course in COVID19 Patients
In the context of the COVID19 pandemic and containment, chest CT is currently frequently performed on admission, looking for suggestive signs and basic abnormalities of COVID19 compatible viral pneumonitis pending confirmation of identification of viral RNA by reverse-transcription polymerase chain reaction(PCR), with a reported sensitivity of 56-88% in the first …
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- 19 Feb, 2024
- 1 location
A Longitudinal Study of COVID-19 Sequelae and Immunity
Some people who get COVID-19 have only mild symptoms. But for others, infection leads to pneumonia, respiratory failure, and, in some cases, death. Researchers want to learn more about any effects that may persist after people recover from COVID-19.
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- 19 Feb, 2024
- 1 location
Change in the Ratio of Mean Platelet Volume (MPV) to Platellet(PLT) in Covid-19 Pneumonia Patients
Previous studies claims that the proportion of mean platellet volume to platellet which can simply be determined with simple blood tests that are performed at admission, might predict the mortality in ARDS patients. Covid-19 pneumonia has a very similar clinical outlook with ARDS. Therefore we decided to research whether that …
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- 19 Feb, 2024
- 1 location
Anti-SARS-CoV-2 Inactivated Convalescent Plasma in the Treatment of COVID-19
This is an obsevational study, the investigators collected the clinical information and clinical outcomes of the COVID-19 patients using anti-2019-nCoV inactivated convalescent plasma.The study is to evaluate the efficacy and safety of anti-2019-nCoV inactivated convalescent plasma in the treatment of COVID-19 pneumonia.
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- 19 Feb, 2024
- 1 location