Found 1700 clinical trials
Malnutrition in Chronic Gastrointestinal Diseases Cross-sectional Study
Malnutrition and muscle wasting are common consequences of life-threatening, chronic diseases of the gastrointestinal tract. Such diseases include liver cirrhosis, chronic pancreatitis and short bowel syndrome. Malnutrition and muscle wasting increase the risk of complications, reduce the life expectancy and impair the quality of life. The development of malnutrition and …
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- 19 Feb, 2024
Investigation of the Respiratory Profile of Patients With Obstructive Pulmonary Disease (ASTHMA, COPD) (OPTIPULM)
The primary aim of the OPTIPULM study is the evaluation of recorded pulmonary function curves and, based on them, the computer modelling of lung deposition for the individually used or potentially applicable inhalation drugs. The secondary aims include assessing the patients' inhalation device usage and providing recommendations for its optimization …
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- 12 May, 2025
Natural History Study of Children and Adults With Neuroendocrine Neoplasms (NEN)s
Background Neuroendocrine neoplasms (NENs) are rare tumors that originate in neuroendocrine cells. NENs can affect almost any part of the body. People with low-grade tumors can live many years. But high-grade tumors can be very aggressive. Researchers want to learn more about this type of cancer. This may help them …
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- 19 Feb, 2024
Biomarkers in Polyradiculoneuropathies
The nodes of Ranvier contain ion channels that enable the rapid propagation of the nerve impulse. Cell adhesion molecules and glycolipids play an important role in the formation of the nodes of Ranvier. Antibodies against glycolipids are detected in half of patients with Guillain-Barr syndrome, an acute inflammatory neuropathy affecting …
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- 19 Feb, 2024
Influence of Hormone Treatment in Radiation Therapy for Bladder Cancer
Bladder cancer is often treated with cystectomy or radiation therapy. Following radiation therapy patients will often have severe side effects from the treatment. Studies have suggested that simultanously treatment with androgen deprivation therapy during radiation therapy may be able to proctect stemcells in the bladder, thus improving tissue recovering post-radiation, …
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- 19 Feb, 2024
Early Detection of Cardiac Damage by Two Dimensional Speckle Tracking Echocardiography After Thoracic Radiation Therapy
The purpose of this study is to detecte and predict early subclinical cardiac damage induced by thoracic radiation therapy based on twodimensional speckle tracking echocardiography combined with multiple circulating biomarkers.
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- 19 Feb, 2024
Cerebral Morbidity After Radiation Therapy for Brain Tumors
This study will assess cognitive function in patients with a primary brain tumour treated with radiation therapy (RT) to generate radio-sensitivity and volume effect parameters for the development of cognitive dysfunction. All types of brain tumours apart from glioblastoma will be included.
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- 19 Feb, 2024
Risk Prediction and Therapy Monitoring in Patients With SARS-Cov-2 Infection / COVID 19
Approximately 15% of patients with SARS-CoV-2 infection / COVID-19 develop a severe clinical course. This leads to hospitalization and potentially life threatening complications such as pneumonia and respiratory failure. Predictors for early detection and risk stratification are urgently needed. Moreover, only scarce information is available for long-term follow-up and late …
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- 19 Feb, 2024
Assessment of Salivary GM-CSF, MIP, and IL-1β Levels in Subjects With Varying Periodontal Conditions
In order to determine the pathogenesis of chronic inflammatory diseases, the levels of various cytokines are examined in tissues and fluids taken from the body. In recent publications, the role of Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF), Macrophage Inflammatory Protein (MIP)-1α and Interleukin (IL)-1β on chronic inflammatory diseases has been investigated. …
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- 08 May, 2025
Optimizing Y90 Therapy for Radiation Lobectomy
HCC resection candidates with inadequate future liver remnant will be enrolled in this study. They will be treated with Y90 radioembolization to help grow the liver enough to undergo liver resection. There will be 2 Patient Groups. The first group of patients will be treated with Y90 dose and embolic …
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- 19 Feb, 2024