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Found 1339 clinical trials
Luxembourg Cohort of Positive Patients for COVID-19: a Stratification Study to Predict Patient Prognosis

Predi-COVID is a prospective cohort study composed of people positively tested for COVID-19 in Luxembourg, followed digitally for monitoring participants' health evolution and symptoms at home. Participants will be actively followed for 14 days from the time of confirmation of diagnosis, whether they are at the hospital or at home …

acute respiratory syndrome (sars)
SARS
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  • 19 Feb, 2024
ICG Fluorescence Imaging in Lower Extremity Amputation Patients

This is a non-randomized prospective study of 30 patients scheduled to undergo lower extremity amputation (below the knee, through the knee or above the knee) evaluating bone perfusion and viability using indocyanine green (ICG) fluorescence imaging at several steps during surgical procedure.

fluorescence imaging
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  • 19 Feb, 2024
ICG Fluorescence Imaging in Trauma Patients

This will be a prospective observational trial to better understand the range and variation associated with bone/soft tissue perfusion in fracture patients and examine the relationship between perfusion, measured using quantitative Indocyanine green (ICG) fluorescence and complications such as surgical site infection (SSI), persistent SSI, and fracture nonunion.

fracture care
debridement
wound care
fluorescence imaging
internal fixation
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  • 19 Feb, 2024
Deciphering AMD by Deep Phenotyping and Machine Learning- Prospective Study - PINNACLE

We will conduct a prospective non-interventional study including 400 early AMD patients (=600 untreated early AMD eyes, including both unilateral (AREDS IV) and bilateral (AREDS II)) over 3 years to specifically investigate the morphological sequence of events preceding the conversion towards late AMD. All patients will be followed by OCT …

atrophy
mydriasis
drusen
geographic atrophy
neovascularization
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  • 19 Feb, 2024
Natural History Study of MNGIE

Non-interventional, prospective, multicenter, natural history study of patients with mitochondrial neurogastrointestinal encephalomyopathy (MNGIE)

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  • 19 Feb, 2024
RASopathy Biorepository

The RASopathies are a group of developmental disorders caused by genetic changes in the genes that compose the Ras/mitogen activated protein kinase (MAPK) pathway. New RASopathies are being diagnosed frequently. This pathway is essential in the regulation of the cell cycle and the determination of cell function. Thus, appropriate function …

heart defects
genetic testing
cancer
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  • 19 Feb, 2024
Plaque Stratification Using Ccta in Coronary ARtery Disease (PoSTCARD)

Develop time-to-event prediction and plaque phenotype classification models for patients with known or suspected coronary artery disease.

arterial disease
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  • 19 Feb, 2024
Biomarkers of CASH

The project aims to develop prognostic and diagnostic blood tests for symptomatic brain hemorrhage in patients diagnosed with cavernous angiomas, a critical clinical challenge in a disease affecting more than a million Americans. We further examine whether blood biomarkers can replace or enhance the accuracy of advanced imaging in association …

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  • 19 Feb, 2024
Improving Colonoscopy Quality for Colorectal Cancer Screening in the National VA Healthcare System

High quality screening colonoscopy is critical for colorectal cancer (CRC) prevention in Veterans. There is significant variability in colonoscopy quality in VA that is directly linked to differences in CRC incidence and death. The investigators developed the VA Endoscopy Quality Improvement Program (VA-EQuIP) that the National GI program office will …

colorectal cancer
cancer screening
colorectal cancer screening
screening colonoscopy
adenoma
  • 0 views
  • 19 Feb, 2024
Development of an Algorithm to Differentiate Heart Murmurs Using Electronic Stethoscopes

The Eko CORE and DUO stethoscopes are FDA-approved electronic devices that have the capacity to record heart sounds. The study seeks to expand murmur detection to include VHD classification through the development of novel ML algorithms that are able to distinguish between systolic vs. diastolic vs. continuous murmurs, as well …

heart sounds
auscultation
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  • 19 Feb, 2024