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Found 1305 clinical trials
TRACK-MSA: A Longitudinal Study to Define Outcome Measures in Multiple System Atrophy

TRACK-MSA is an observational, non-interventional, longitudinal natural history study to define changes in clinical, neurological, blood, CSF, and neuroimaging biomarkers in patients with multiple system atrophy (MSA) comparing baseline to 6-month and 1-year assessments. The study will enroll 50 patients with MSA-P or MSA-C at 2 or more participating sites.

brain mri
mri brain
atrophy
  • 0 views
  • 19 Feb, 2024
  • 1 location
Characterization of the Clinical-epidemiological Profile of Patients With SMA5q Types II and III: Observational Study

This study aims to characterize the clinical-epidemiological profile and baseline characteristics of patients with spinal muscular atrophy (SMA) 5q types II and III in follow-up at the Brazilian Unified Public Health System (SUS). The study data will be based on patients medical records from several Brazilian public hospitals, which will …

nusinersen
spinal muscular atrophy
muscle atrophy
atrophy
  • 0 views
  • 19 Feb, 2024
  • 9 locations
One-Year Quality of Life and Functional Prognosis of COVID-19 Patients in Post-ICU Setting

Ancillary studies aim to assess the course of muscle function (atrophy, structural modifications), lung function (loss of aeration) and safety of early mobilization.

weakness
pulmonary function tests
covid-19
atrophy
lung function
  • 0 views
  • 19 Feb, 2024
  • 3 locations
Monitoring of Metabolic Adverse Events of Second Generation Antipsychotics in a Naive Pediatric Population

Introduction: Second Generation Antipsychotics (SGAs) are widely used in the pediatric population. It is currently established that SGAs may induce undesirable metabolic adverse events (AEs) such as weight gain, metabolic changes in blood lipids or glucose with risk of potential cardiovascular morbidity and mortality. The Canadian Alliance for Monitoring Effectiveness …

hematology test
pediatric
blood test
  • 0 views
  • 19 Feb, 2024
  • 1 location
Community-based Cohort of Functional Decline in Subjective Cognitive Complaint Elderly

Background With the global population aging and life expectancy increasing, dementia has turned a priority in the health care system. In Chile, dementia is one of the most important causes of disability in elderly, corresponding nearly to 40% of cases, and the most rapidly growing cause of death in the …

mild cognitive impairment
dementia
frontotemporal lobar degeneration
cognitive impairment
demented
  • 0 views
  • 19 Feb, 2024
  • 1 location