Found 153 clinical trials
Optimal EGFR TKIs Treatment Strategies for Lung Adenocarcinoma Harboring EGFR Exon 19 Deletion Variants
To determine the optimal EGFR TKIs treatment strategies for lung adenocarcinoma harboring EGFR exon 19 deletion variants
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- 19 Feb, 2024
Impact of Respiratory Virus in Critically Ill Patients With Acute Respiratory Failure
This is an observational study to evaluate the clinical impact of respiratory virus in the patients with acute respiratory failure
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- 19 Feb, 2024
A Study of Patients With Chronic Disease
TARGET-RWE is a 10-year, international, longitudinal, observational study of patients with chronic disease designed to specifically address important clinical questions that remain incompletely answered from registration trials. The protocol will follow a master protocol design in which a shared study infrastructure supports progressive development of the registry across the spectrum …
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- 19 Feb, 2024
Outcome of COVID-19 Patients After Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome
This study aims to investigate outcomes and predictors of outcome after extracorporeal membrane oxygenation (ECMO) therapy for severe acute respiratory syndrome (ARDS) in COVID-19 patients.
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- 19 Feb, 2024
Data Collection of Standard Care and Evaluation of NHLBI Patients and Donors
Eligibility People age 2 and older who have or are suspected to have a medical condition for which they have been referred to NIH s National Heart, Lung, and Blood Institute, as well as stem cell donors Design Participants may be screened with a review of the following: Medical records …
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- 19 Feb, 2024
Pharmacokinetics Pharmacodynamics and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
The study investigators are interested in learning more about how drugs, that are given to children by their health care provider, act in the bodies of children and young adults in hopes to find the most safe and effective dose for children. The primary objective of this study is to …
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- 19 Feb, 2024
COVID-19 and Cancer Patients
Routinely collected data will be used to assess the morbidity and mortality of cancer patients following a positive COVID-19 infection.
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- 19 Feb, 2024
Genetics of COVID-19 Susceptibility and Manifestations
Background The current SARS-CoV-2 pandemic presents a serious challenge to public health. Some people who are infected with SARS-CoV-2 have mild symptoms or none at all. But others develop severe symptoms, like pneumonia or organ failure. Researchers think that people s genes might play a role in how sick they …
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- 19 Feb, 2024
A Study to Identify Errors in Inhaler Technique in Adults
This study will observe the inhaler technique of people using 13 different inhaler types; record any technique errors being made against checklists developed for each inhaler device based on their manufacturer's guidelines, and reeducate any observed inhaler technique errors as required.
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- 19 Feb, 2024
RASopathy Biorepository
The RASopathies are a group of developmental disorders caused by genetic changes in the genes that compose the Ras/mitogen activated protein kinase (MAPK) pathway. New RASopathies are being diagnosed frequently. This pathway is essential in the regulation of the cell cycle and the determination of cell function. Thus, appropriate function …
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- 19 Feb, 2024