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Found 133 clinical trials
Study to Evaluate the Safety Tolerability Pharmacokinetics and Pharmacodynamics of CC-94676 in Subjects With Metastatic Castration-Resistant Prostate Cancer

This is a first in human study to assess the safety, tolerability, PK, PD and preliminary efficacy of CC-94676 in men with progressive metastatic castration-resistant prostate cancer.

adenocarcinoma of prostate
abiraterone
prostate cancer
gonadotropin releasing hormone
luteinizing hormone
  • 0 views
  • 19 Feb, 2024
  • 6 locations
Study of PSMA PET/MR Guided Stereotactic Body Radiation Therapy With Simultaneous Integrated Boost (SBRT-SIB) for High-Intermediate and High Risk Prostate Cancer

This is a single-arm Phase II clinical trial assessing the clinical efficacy of prostate specific membrane antigen (PSMA) PET/MR guided MR-LINAC based SBRT-SIB with planned accrual of 50 patients.

adenocarcinoma of prostate
stereotactic body radiation therapy
metastasis
hbed-cc
adenocarcinoma
  • 16 views
  • 19 Feb, 2024
  • 1 location
Cost Talk: Discussing Cancer Care Costs

The purpose of this study is to investigate whether an encounter decision aid (used during a consultation) containing cost information about options, combined with clinician training about cost discussions and available financial resources, influence surgeon-patient cost conversations, referrals to address costs, patients' financial stress, and high-quality decision-making for patients with …

cancer care
prostate specific antigen
  • 0 views
  • 19 Feb, 2024
  • 1 location
5 Fractions of Pelvic SABR With Intra Prostatic SABR Boost:

5-fraction SABR is a feasible, well-tolerated, effective and cost effective treatment for high-intermediate and high risk prostate cancer with/without an image-guided intraprostatic boost.

adenocarcinoma
adenocarcinoma of prostate
stereotactic body radiation therapy
  • 0 views
  • 19 Feb, 2024
  • 1 location
Tasquinimod for the Treatment of Relapsed or Refractory Myeloma

This study is the first study of tasquinimod, an inhibitor of S100A9, in patients with multiple myeloma.

measurable disease
multiple myeloma
  • 0 views
  • 19 Feb, 2024
  • 1 location
Lutetium-177-PSMA Radioligand Therapy in Advanced Salivary Gland Cancer Patients

Phase 2 pilot study, which evaluates the safety and efficacy of Lutetium-177-PSMA radioligand therapy in advanced salivary gland cancer patients.

adenoid cystic carcinoma
measurable disease
neutrophil count
metastasis
liver metastasis
  • 0 views
  • 19 Feb, 2024
  • 1 location
Prostate Screening for Men With Inherited Risk of Developing Aggressive Prostate Cancer PATROL Study

This study investigates ways to detect prostate cancer earlier in men who are at increased genetic risk of developing prostate cancer that forms, grows, or spreads quickly (aggressive).

measurable disease
adenocarcinoma of prostate
digital rectal examination
cancer therapy
prostate carcinoma
  • 0 views
  • 19 Feb, 2024
  • 1 location
CT-guided Stereotactic Body Radiation Therapy and MRI-guided Stereotactic Body Radiation Therapy for Prostate Cancer MIRAGE Study

This phase III trial studies compares CT-guided stereotactic body radiation therapy and MRI-guided stereotactic body radiation therapy (SBRT) in treating prostate cancer. Image-guided SBRT is a standard treatment for prostate cancer, which combines imaging of the cancer within the body with the delivery of therapeutic radiation doses produced on a …

adenocarcinoma of prostate
stereotactic body radiation therapy
metastasis
prostate cancer
adenocarcinoma
  • 0 views
  • 19 Feb, 2024
  • 1 location
Multiple Myeloma and Environmental Exposure to Pesticides in the French West Indies: A Population Based Case-control Study.

Multiple myeloma (MM) is a malignancy of plasma cells engaging in monoclonal immunoglobulin production. A strong presumption was established between exposure to pesticides and the risk of MM. The French West Indies departments of Guadeloupe and Martinique are characterized by a wide use of pesticides related to bananas plantation, particularly …

monoclonal protein
cancer
monoclonal antibodies
immunoglobulins
multiple myeloma
  • 0 views
  • 19 Feb, 2024
  • 2 locations
Impact of DNA Repair Pathway Alterations on Sensitivity to Radium-223 in Bone Metastatic Castration-resistant Prostate Cancer

This phase II study investigates how well radium-223 works in treating patients with castration-resistant prostate cancer than has spread to the bones (bone metastases). Prostate cancer is the most common cancer in men and the second leading cause of cancer death.

metastasis
stage ivb prostate cancer ajcc v8
prostate cancer
prostate carcinoma
bone metastases
  • 0 views
  • 19 Feb, 2024
  • 1 location