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Found 657 clinical trials
Trial of Encapsulated Rapamycin (eRapa) for Bladder Cancer Prevention

eRapa (encapsulated rapamycin) will be investigated for secondary prevention in patients with diagnosed non-muscle invasive bladder cancer (NMIBC) through a phase II double-blind randomized controlled trial of long-term (one year) prevention with eRapa versus placebo.

  • 2 views
  • 19 Feb, 2024
Histopathologic Effect of Calcium Electroporation on Cancer in the Skin

In this phase II study we investigate the effect of calcium electroporation on cancer in the skin investigated by histopathology.

cancer
endocrine therapy
metastasis
calcium
hormone therapy
  • 0 views
  • 19 Feb, 2024
Sentinel Lymph Node Biopsy With Hybrid Technique in Breast Cancer

Sentinel lymph node (SLN) biopsy is the gold standard method to stage axilla in breast cancer. The aim of the study is to compare the efficiency of various methods to identify SLN is breast cancer patients.

sentinel node
excisional biopsy
sentinel lymph node biopsy
  • 0 views
  • 19 Feb, 2024
Hypofractionation And Ultra-Hypofractionation In Adjuvant Radiotherapy For Breast Cancer

Prospective randomized study comparing 5 fractions in alternative days to standard 15 fractions regarding effectiveness and feasibility during adjuvant treatment in breast caner patients aged above 50 years

stage iv breast cancer
invasive breast cancer
immunomodulators
ct scan
ct scan chest
  • 0 views
  • 19 Feb, 2024
AMG 510 Ethnic Sensitivity Study (CodeBreak 105).

To evaluate safety, tolerability, PK, and preliminary efficacy of AMG 510 PO QD in subjects of Chinese descent with KRAS p.G12C-mutant advanced/metastatic solid tumors.

  • 0 views
  • 19 Feb, 2024
Stem Cell Transplant From Donors After Alpha Beta Cell Depletion in Children and Young Adults

Initially this device will be used in a single-center, open-label, single-arm, phase II clinical trial to evaluate the efficacy of haploidentical PBSC grafts depleted of TCR/+ and CD19+ cells using the CliniMACS TCR/CD19 System in children and adults with hematological and non-hematological malignancies.

renal function
congestive heart failure
graft versus host disease
hla-a
immunosuppression
  • 0 views
  • 19 Feb, 2024
Phase 2 Trial in Multiple Brain Metastases Outcomes With HA-SIB-WBRT

With improvements in radiation technology, advanced dose-painting techniques now allow a simultaneous integrate boost (SIB) dose to lesions whilst minimising doses to the hippocampus to potentially improve brain tumour control and preserve cognitive outcomes (HA-SIB-WBRT). The Investigators believe that the SIB in HA-SIB-WBRT (experimental) will result in better functional and …

primary malignant neoplasm
edema
brain tumor
brain metastasis
stereotactic radiosurgery
  • 0 views
  • 19 Feb, 2024
Anti-GITR/Anti-PD1/Stereotactic Radiosurgery in Recurrent Glioblastoma

The investigators hypothesize that the proposed regimen will be safe and stimulate a robust anti-tumor immune response and result in improved tumor responses.

vegf
glioblastoma multiforme
recurrent tumor
brain surgery
gliosarcoma
  • 0 views
  • 19 Feb, 2024
Multimodality Treatment in Stage III Non-small Cell Lung Cancer (NSCLC)

Radiotherapy is thought to act synergistically with immunotherapy through release of tumor antigens and modulation of the local immune microenvironment in favor of a better antigen-presentation and (systemic) anti-tumor immune response (abscopal effect).

immunomodulators
platelet count
pulmonary function tests
non-small cell lung cancer
adjuvant therapy
  • 0 views
  • 19 Feb, 2024
Thoracic Re-irradiation For Locoregionally Recurrent Non-small Cell Lung Cancer

This prospective phase II study is to assess the efficacy and safety of thoracic re-irradiation for locoregionally recurrent non-small cell lung cancer using hypofractionated technique.

  • 0 views
  • 19 Feb, 2024