Found 141 clinical trials
Pharmacokinetics Pharmacodynamics and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
The study investigators are interested in learning more about how drugs, that are given to children by their health care provider, act in the bodies of children and young adults in hopes to find the most safe and effective dose for children. The primary objective of this study is to …
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- 19 Feb, 2024
Pulmonary Embolism Prognosis Model
The purpose of this study is to analyze the clinical manifestations, imaging features, and prognosis-related factors of pulmonary embolism, and to explore the prognosis risk assessment model for Chinese patients
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- 19 Feb, 2024
The ATtune Knee Outcome Study
To accomodate dissatisfied patients with a total knee arthroplasty (TKA) and improve outcomes, several knee systems have been developed. The cemented ATTUNE TKA shows superiority over other established knee systems at short-term, abating with longer follow-up. There have been no studies reporting on the results of the uncemented version of …
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- 19 Feb, 2024
Predictors of Better Outcomes After Severe Acquired Brain Injuries
Severe Acquired Brain Injury is defined as a traumatic, post-anoxic, vascular or other brain damage that causes coma for at least 24 hours and leads to permanent disability with sensorial, motor, cognitive or compartmental impairment. In this context, an accurate characterization of individual patients' profile in terms of neuronal damage, …
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- 19 Feb, 2024
Place of Intrathecal Analgesia to Improve the Quality of Life of Painful Cancer Patients
The intrathecal analgesia is a recommended technic to treat persistent pain in cancer patient but little used, whose the technical conditions require hospital multidisciplinary expertise and coordination associated to a link between city and hospital.
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- 19 Feb, 2024
Bone Pain in Multiple Myeloma- a Translational Study
Primary research questions: How is the bone pain experienced by myeloma patients (intensity, location and type of pain) and how does it affect their quality of life? Do myeloma cells induce changes in the density and/or location of nerve fibres innervating the bone, and if so, are these correlated to …
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- 19 Feb, 2024
To Study the Association Among Labor Pain and Physical Parameters in Laboring Pregnant Women
Important monitored parameters include, fetal heartbeat, uterine contractions, oxygen saturation and blood pressure, among others.1 During labor, uterine contractions can cause pain.3 This pain may be measured using a visual analogue scale (VAS).2 The pain from uterine contractions promotes the release of hormones including cortisol which can cause decreased or …
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- 19 Feb, 2024
Comparing Sensory Modulation Anxiety and Quality of Life Between Children With Primary Headaches and Healthy Peers
Study hypotheses: Children with headaches will show significantly higher sensory reactivity, higher anxiety level and lower quality of life that health controls. Among children with headaches, sensory reactivity will significantly correlate with higher anxiety level and lower quality of life. Among children with headaches quality of life will be predicted …
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- 19 Feb, 2024
The Effect of Pediatric Patient Temperament on Postoperative Outcomes
These data will be used to determine if patients with a specific temperament profile are more likely to experience increased pain, emergence agitation, emotional changes, and behavioral disturbances postoperatively.
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- 19 Feb, 2024
ASHCOM Shoulder System and Its Related Instruments
The objectives of this study are to confirm safety, performance and clinical benefits of the ASHCOM Shoulder System and its related instruments by analysis of standard scoring systems, radiographs and adverse event records.
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- 19 Feb, 2024