Found 1327 clinical trials
A Clinical Study of Pyrotinib in Patients of Advanced Colorectal Cancer With Her2 Variation
To Observe the Efficacy and Safety of Pyrotinib Maleate in Patients With Advanced HER2 Variation Colorectal Cancer
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- 19 Feb, 2024
- 1 location
Epidemiological Study of the Microbiota in Critically Ill Children (n=100) From 1 to 16 Years Compared With Healthy Controls (n=50) and Its Relationship With Clinical Complications and Inflammatory Biomarkers
Objectives: To study the composition of the microbiota in critically ill children, and to know the relationship of its microbiota with clinical complications and inflammation biomarkers. Design: Multicenter observational and prospective study including 100 critically ill children admitted in three pediatric intensive care units with a prediction of more than …
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- 19 Feb, 2024
- 1 location
Evaluating Cascade Communication Methods
Hereditary cancer programs face challenges with respect to effective communication of genetic test results within families and uptake of genetic testing by relatives. This study aims to determine if a "disclosure toolkit" provided to the index participant (carrier of cancer risk gene mutation) contributes to sharing genetic test results with …
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- 19 Feb, 2024
- 1 location
Long-term Outcome After Gestational Diabetes and Diabetes in Pregnancy
The primary objectives of the proposed project are to assess the long-term effects of prenatal exposure to gestational diabetes or diabetes on the maturation and health of the offspring. In addition, the long-term changes on the health of the affected mothers will be investigated, taking into account the metabolic adjustment …
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- 19 Feb, 2024
- 1 location
A Prospective Single-Center Evaluation of SureForm Staplers in Robotic-assisted Colorectal Procedures
The primary objective of this study is to evaluate the performance of SureForm Staplers (60 and 45) for transection and/or creation of anastomosis during robotic-assisted colorectal procedures.
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- 19 Feb, 2024
- 1 location
Effects on the Qt Interval of COVID-19 Coronavirus Infection
The present study aims to evaluate the impact of COVID-19 disease and its treatment on ventricular repolarization, assessed by measuring the QTc interval, in patients admitted to the critical care unit.
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- 19 Feb, 2024
- 1 location
Retrospective Analysis of Sarcopenia in Older Patients Undergoing Laparotomy
Assess the influence of sarcopenia on outcomes of emergency laparotomy in the over 65 age group
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- 19 Feb, 2024
- 1 location
Prospective Longitudinal Cohort Study of Vasculitis Patients
VASCO is a prospective observational cohort study which aim to describe the presentation, comorbidities, management, outcomes and damage of vasculitis patients, from the analysis of the clinical, biological and immunological data.
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- 19 Feb, 2024
- 1 location
Influenza Vaccination in Patients Living With HIV in the Northern Region
Anyone living with the Human Immunodeficiency Virus (HIV) has an indication for annual influenza vaccination. (Vaccination schedule and vaccination recommendations 2019). Influenza is a viral infection that has a significant impact on the health care system. However, vaccination coverage in France is still insufficient with regard to the objectives set …
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- 19 Feb, 2024
- 1 location
PHenotyping patiENts Admitted to Hospital With cOvid-19 Infection and idenTifYing Prognostic markErs
PHENOTYPE is an investigator-led, observational cohort study which aims to explore the long-term outcomes of patients with COVID-19 infection and to identify potential risk factors and biomarkers that can prognosticate disease severity and trajectory.
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- 19 Feb, 2024
- 1 location