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Found 1270 clinical trials
Sleep-disordered Breathing in Infants With Myelomeningocele

This study aims to determine whether the risk for sleep-disordered breathing in infants with myelomeningocele (a severe form of spina bifida) differs among those who underwent fetal vs. postnatal surgery, and to examine the link between sleep-disordered breathing and neurodevelopment.

polysomnography
sleep-disordered breathing
spina bifida
  • 0 views
  • 19 Feb, 2024
  • 7 locations
Mechanisms of Hypoglycemia in Patients Without Diabetes

The goal of this study is to identify physiologic and molecular mechanisms that underlie hypoglycemia in the absence of diabetes (or medications that can cause hypoglycemia) and to investigate potential genetic and microbiome differences which contribute to hypoglycemia. We will test the hypothesis that hypoglycemia in the absence of diabetes …

hypoglycemia
genetic variation
continuous glucose monitoring
gastrointestinal surgery
diabetes
  • 0 views
  • 19 Feb, 2024
  • 1 location
Seroconversion Among Staff at a Large Acute Care Hospital in Denmark During the COVID-19 Pandemic

The aim of this study is to apply serology testing methods for SARS-CoV2 antibodies in samples collected from HCWs in an acute hospital. This will enable the identification of those who are protected and non-infectious for SARS-CoV2 and those who are seronegative and therefore potentially susceptible and infectious on patient …

SARS
covid-19
acute respiratory syndrome (sars)
  • 0 views
  • 19 Feb, 2024
  • 2 locations
TORNADO-Omics Techniques and Neural Networks for the Development of Predictive Risk Models

The goal of this observational study is to define a personalized risk model in the super healthy and homogeneous population of Italian Air Force high-performance pilots. This peculiar cohort conducts dynamic activities in an extreme environment, compared to a population of military people not involved in flight activity. The study …

  • 0 views
  • 02 Apr, 2026
Evaluating the Role of Inflammation in Neonatal Epileptogenesis

The purpose of this study evaluate the relationship between inflammation and epilepsy in neonates with seizures after birth.

encephalopathy
eeg monitoring
seizure
inflammatory response
epilepsy
  • 0 views
  • 19 Feb, 2024
  • 4 locations
Postoperative Neurocognitive Disorders

The purpose of this study is to examine the mechanisms of brain injury contributing to postoperative neurocognitive disorders (PNCD) in an at-risk population (obstructive sleep apnea (OSA)) undergoing surgery. The investigators will enroll 50 OSA patients scheduled for surgery. All patients will have a brain scan (fMRI) within five days …

brain scan
polysomnography
apnea-hypopnea index
neurocognitive disorders
apnea
  • 0 views
  • 19 Feb, 2024
  • 1 location
Different Susceptibility to SARS CoV-2 Infection Among Health Care Workers Highly Exposed to COVID-19.

The primary objective of this study is to establish differences in susceptibility to SARS CoV-2 infection among health care workers (HCW) highly exposed to patients with COVID-19 diagnosis. To ascertain this issue, we evaluated: Changes in receptor polymorphism (ACE2 and CD26 receptor study. SARS-CoV-2 CD4/CD8 T cell response (CTL) Different …

  • 0 views
  • 19 Feb, 2024
  • 1 location
Plenvu 1 - Questionnaire Study Exploring Patients Preference in Bowel Preparation Timings for Morning Colonoscopy

Questionnaire study exploring patients preference in bowel preparation timings for morning colonoscopy.

plenvu
endoscopy
  • 0 views
  • 19 Feb, 2024
  • 1 location
Asthma: Phenotyping Exacerbations 2

The main outcomes of this study are to establish a cohort of well-phenotyped asthma patients with a recent history of an exacerbation. We aim to describe exacerbation profiles (phenotypes) of the cohort in terms of inflammatory/biomarker profile and bacterial/viral infection status and to compare these with exacerbation events in the …

corticosteroids
spirometry
skin prick
maintenance therapy
prick skin
  • 0 views
  • 24 Nov, 2025
  • 1 location
Asthma: Phenotyping EXacerbations

The main outcomes of this study are to establish a cohort of well-phenotyped asthma patients with a recent history of an exacerbation. We aim to describe exacerbation profiles (phenotypes) of the cohort in terms of inflammatory/biomarker profile and bacterial/viral infection status and to compare these with exacerbation events in the …

corticosteroids
spirometry
skin prick
maintenance therapy
prick skin
  • 0 views
  • 19 Feb, 2024
  • 1 location