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Found 1226 clinical trials
Decitabine With Ruxolitinib or Fedratinib for the Treatment of Accelerated/Blast Phase Myeloproliferative Neoplasms

This phase II trial studies how well decitabine with ruxolitinib or fedratinib works before hematopoietic stem cell transplant in treating patients with accelerated/blast phase myeloproliferative neoplasms (tumors). Drugs used in chemotherapy, such as decitabine, work in different ways to stop the growth of tumor cells, either by killing the cells, …

myeloproliferative disorder
blood count
myelodysplastic syndromes
myelodysplastic/myeloproliferative neoplasms
fedratinib
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  • 19 Feb, 2024
Study of Decitabine Combined With HAAG Regimen in Newly Diagnosed ETP-ALL/LBL T/M-MPAL and ALL/LBL With Myeloid or Stem Cell Markers Patients

The purpose of this study is to evaluate the efficacy and safety of decitabine combined with HAAG regimen in the treatment of newly diagnosed patients with ETP-ALL/LBL, T/M-MPAL and ALL/LBL with myeloid or stem cell markers.

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  • 19 Feb, 2024
Azacitidine Venetoclax and Trametinib for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia or Higher-Risk Myelodysplastic Syndrome

This phase II trial investigates how well azacitidine, venetoclax, and trametinib work in treating patients with acute myeloid leukemia or higher-risk myelodysplastic syndrome that has come back (relapsed) or has not responded to treatment (refractory). Chemotherapy drugs, such as azacitidine, work in different ways to stop the growth of cancer …

myelodysplastic syndrome
refractory aml
refractory chronic myelomonocytic leukemia (cmml)
recurrent chronic myelomonocytic leukemia
hemolysis
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  • 19 Feb, 2024
Register of Blood Stem Cell Transplantation

Register of patients with blood stem cell transplantations (autologous, allogen).

cell transplantation
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  • 19 Feb, 2024
The Acute Promyelocytic Leukaemia Asian Consortium (APL-AC) Project

There is currently lack of collaborative data on the epidemiology, clinicopathologic features and treatment outcome of newly diagnosed and relapsed APL in Asia. In addition, there is lack of data comparing oral- As2O3-based regimens with other treatment approaches, including intravenous As2O3,in the frontline or relapsed setting. With the long-term data …

leukemia
acute promyelocytic leukemia
rara translocation
acute myeloid leukemia
arsenic
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  • 19 Feb, 2024
Role of aGVHD Biomarkers on aGVHD Risks

To establish risk rating criteria of biological protein marker, determine the role and consistency of aGVHD biomarkers in aGVHD diagnosis and aGVHD prognosis, and evaluate the the impact on non-relapse mortality and relapse and disease free survival, the multicenter study on aGVHD biomarkers detection in the patients underwent allogeneic hematopoietic …

allogeneic hematopoietic stem cell transplantation
hematologic malignancies
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  • 19 Feb, 2024