Found 1383 clinical trials
Impact of Sinus Surgery on Individuals With Cystic Fibrosis
This study will be a prospective, observational study of patients who undergo endoscopic sinus surgery for cystic fibrosis-related chronic rhinosinusitis (CRS).
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- 19 Feb, 2024
- 1 location
Characterization of the Clinical-epidemiological Profile of Patients With SMA5q Types II and III: Observational Study
This study aims to characterize the clinical-epidemiological profile and baseline characteristics of patients with spinal muscular atrophy (SMA) 5q types II and III in follow-up at the Brazilian Unified Public Health System (SUS). The study data will be based on patients medical records from several Brazilian public hospitals, which will …
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- 19 Feb, 2024
- 9 locations
Streamlining the Efficiency of PrEP Implementation
This is a pilot facility-based direct-to-pharmacy PrEP refill delivery to streamline care pathway in Kenyan public health HIV facilities implementing PrEP. Data on up to 500 PrEP users will be evaluated to understand delivery efficiency and in-depth interview with users and delivery key informants will be conducted to identify barriers …
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- 19 Feb, 2024
- 1 location
Cardiac Biomarkers in Preeclampsia: Prediction of Disease and the Risk of Future Cardiovascular Events in Survivors
Data Analysis: would be performed using the Statistical Package for Social Sciences (SPSS) software version 21.0. Numerical data would be expressed as mean standard deviation (SD).
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- 19 Feb, 2024
- 1 location
Assessment of Salivary GM-CSF, MIP, and IL-1β Levels in Subjects With Varying Periodontal Conditions
All oral clinical parameters of 60 systemically healthy individuals (20 healthy, 20 with gingivitis and 20 with periodontitis) who applied to our clinic for routine periodontal control will be measured and saliva samples will be taken from the patients. GM-CSF, MIP-1α and IL-1β (biomarkers emphasizing inflammation in saliva samples) will …
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- 08 May, 2025
Prospective Trial for the Evaluation of Radiogenomics in Advanced Rectal Cancer
In patients with advanced rectal cancer, molecular subtypes will be identified by preoperative biopsy, CT, MRI / PET radiomics analysis, clinical features, and clinical features will be confirmed and compared.
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- 19 Feb, 2024
- 1 location
Natural History Study of Children and Adults With Neuroendocrine Neoplasms (NEN)s
Eligibility People starting at age 3 and older who have or are suspected of having NENs and are enrolled in protocol 19C0016, Natural History and Biospecimen Acquisition Study for Children and Adults with Rare Solid Tumors Design Participants will be screened with questions about their medical history. This may be …
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- 19 Feb, 2024
- 1 location
Metabolomic and Proteomic Fingerprinting in Peri-implant Diseases
One year after the corresponding treatment is provided, the PICF of the treated implants with peri-implantitis will be sampled again. Both proteomic and metabolomic profiling of the samples will be carried out. The most important strength of this project will be the ability to evaluate together the whole proteome and …
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- 19 Feb, 2024
- 1 location
Postoperative Neurocognitive Disorders
The Confusion Assessment Method (CAM-S) test, will be used to examine postoperative delirium.
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- 19 Feb, 2024
- 1 location
Is COVID-19 Transmitted Through Human Milk? Implications for Breastfeeding and Human Milk Banking-Study 1b
This study seeks to address this public health issue. Donor milk will be collected from the Rogers Hixon Ontario Human Milk Bank at Sinai Health System in Toronto. Samples will be analyzed for the COVID-19 virus specific nucleic acid and antibody in real-time and results will be immediately disseminated to …
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- 19 Feb, 2024
- 1 location