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Found 1327 clinical trials
Heart Failure Monitoring With Eko Electronic Stethoscopes

This proof-of-concept study will evaluate the feasibility of the Eko DUO to measure signals relevant to heart failure (HF) decompensation, as well as the feasibility to develop an algorithm to model hemodynamic filling pressures in HF patients under active decompensation in a cardiac intensive care unit (CICU) or coronary care …

hemodynamic measurements
adhf
decompensated heart failure
acute decompensated heart failure
heart failure
  • 0 views
  • 19 Feb, 2024
  • 1 location
A Naturalistic Study of Functional Impairment for Individuals With ADHD in the Early Morning and Late Afternoon/Evening Hours

This is necessary for two reasons: (1) the current literature on ADHD impairment and functioning is concentrated within elementary school children; and (2) studies of intervention effectiveness are typically concentrated during the school day. This current state of the literature ignores the obvious - as ADHD is a chronic disorder, …

chronic disease
autism
psychosis
pervasive developmental disorder
attention deficit hyperactivity disorder
  • 0 views
  • 19 Feb, 2024
  • 1 location
Development and Analysis of a Stool Bank for Cancer Patients

Although animal models are of use to determine the influences of gut and other microbiota on cancer treatment modalities, they are limited due to differences between mouse and human physiology and immunology, as well as the inherent differences in gut microbial populations between the two mammalian organisms. Therefore, samples obtained …

immunotherapies
pembrolizumab
cancer treatment
cancer immunotherapy
  • 0 views
  • 19 Feb, 2024
  • 2 locations
COVID - AirPollution

In this multicenter prospective study, the investigators will analyze the number of deaths in COVID-19 confirmed cases in geriatric patients according to long-term exposure to air pollution, taking into account confounders such as diabetes, hypertension, age, and BMI. Exposure to air pollution will be estimated as the mean concentration of …

  • 0 views
  • 19 Feb, 2024
  • 11 locations
The Effect of Pediatric Patient Temperament on Postoperative Outcomes

This is a prospective observational study to assess preoperative temperament in pediatric patients undergoing tonsillectomy and adenoidectomy, gather demographic data, intraoperative data regarding surgical and anesthetic technique, and collect immediate postoperative data to assess pain, emergence agitation (EA), parental satisfaction as well as remote postoperative data to assess emotional and …

adenoidectomy
postoperative pain
tonsillectomy
agitation
pain assessment
  • 0 views
  • 19 Feb, 2024
  • 1 location
Trajectory of Microbiota Maturation in Healthy Bern Infants - a Network Approach

Methods: The investigators will recruit 120 pregnant mothers who will be followed as mother-baby pairs until 10 years of age. Infants will be followed clinically to determine adequate growth and development as well as pathology including abdominal pain.

placenta
diabetes
hypertension
microbiota
mass spectrometry
  • 0 views
  • 19 Feb, 2024
  • 1 location
Retention and Durability of the Anterior Zirconia Wing Bridge

The type of zirconia-wing bridge the investigators are researching in this study has two wings which generally have three countersunk holes (meaning that the circumference of the outer portion of the hole is larger than the inner part of the hole). Composite resin (dental filling material) is placed in the …

dental filling
  • 0 views
  • 19 Feb, 2024
  • 1 location
ABCB1/P-glycoprotein Expression Influence on Non-metastatic Osteosarcoma of the Extremities

The histological response to primary chemotherapy will be expressed as a percentage of tumor necrosis. In the case of tumor necrosis above 90% the patient is defined as a "good responder" in case of a lower percentage as a "poor responder".

adriamycin
p-glycoprotein
localized disease
metastatic osteosarcoma
adjuvant therapy
  • 0 views
  • 19 Feb, 2024
  • 17 locations
Effect of FFRCT-angio in Functional Diagnosis of Coronary Artery Stenosis

However, the stenosis severity is not closely corresponding with the hemodynamic significance in coronary arteries. As a result, fractional flow reserve (FFR) with pressure wire measurement was introduced to functionally assess the coronary stenosis.

coronary ct
coronary artery stenosis
quantitative coronary angiography
ischemia
computed tomography angiography
  • 0 views
  • 19 Feb, 2024
  • 1 location
Immunotherapy in Lung Cancer: Treatment After IO Cessation.

Immunotherapy is now a standard of care for first-line and eventually salvage therapy in patients with stage IV NSCLC and as adjuvant after RT-CT for stage III NSCLC. The aim of the study is determining the therapeutic landscape and the reason for immunotherapy cessation.

stage iv non-small cell lung cancer
cancer
carcinoma
melanoma
chemoradiotherapy
  • 0 views
  • 19 Feb, 2024
  • 5 locations