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Found 1327 clinical trials
Heart Failure Monitoring With Eko Electronic Stethoscopes

This proof-of-concept study will evaluate the feasibility of the Eko DUO to measure signals relevant to heart failure (HF) decompensation, as well as the feasibility to develop an algorithm to model hemodynamic filling pressures in HF patients under active decompensation in a cardiac intensive care unit (CICU) or coronary care …

hemodynamic measurements
heart failure
decompensated heart failure
acute decompensated heart failure
adhf
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  • 19 Feb, 2024
A Naturalistic Study of Functional Impairment for Individuals With ADHD in the Early Morning and Late Afternoon/Evening Hours

This is necessary for two reasons: (1) the current literature on ADHD impairment and functioning is concentrated within elementary school children; and (2) studies of intervention effectiveness are typically concentrated during the school day. This current state of the literature ignores the obvious - as ADHD is a chronic disorder, …

attention deficit hyperactivity disorder
autism
psychosis
psychiatric disorder
pervasive developmental disorder
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  • 19 Feb, 2024
COVID - AirPollution

In this multicenter prospective study, the investigators will analyze the number of deaths in COVID-19 confirmed cases in geriatric patients according to long-term exposure to air pollution, taking into account confounders such as diabetes, hypertension, age, and BMI. Exposure to air pollution will be estimated as the mean concentration of …

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  • 19 Feb, 2024
Development and Analysis of a Stool Bank for Cancer Patients

Although animal models are of use to determine the influences of gut and other microbiota on cancer treatment modalities, they are limited due to differences between mouse and human physiology and immunology, as well as the inherent differences in gut microbial populations between the two mammalian organisms. Therefore, samples obtained …

cancer treatment
pembrolizumab
cancer immunotherapy
immunotherapies
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  • 19 Feb, 2024
The Effect of Pediatric Patient Temperament on Postoperative Outcomes

This is a prospective observational study to assess preoperative temperament in pediatric patients undergoing tonsillectomy and adenoidectomy, gather demographic data, intraoperative data regarding surgical and anesthetic technique, and collect immediate postoperative data to assess pain, emergence agitation (EA), parental satisfaction as well as remote postoperative data to assess emotional and …

pain assessment
behavioral disturbances
pediatric
adenoidectomy
agitation
  • 0 views
  • 19 Feb, 2024
Trajectory of Microbiota Maturation in Healthy Bern Infants - a Network Approach

Methods: The investigators will recruit 120 pregnant mothers who will be followed as mother-baby pairs until 10 years of age. Infants will be followed clinically to determine adequate growth and development as well as pathology including abdominal pain.

microbiota
mass spectrometry
diabetes
hypertension
placenta
  • 0 views
  • 19 Feb, 2024
Retention and Durability of the Anterior Zirconia Wing Bridge

The type of zirconia-wing bridge the investigators are researching in this study has two wings which generally have three countersunk holes (meaning that the circumference of the outer portion of the hole is larger than the inner part of the hole). Composite resin (dental filling material) is placed in the …

dental filling
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  • 19 Feb, 2024
ABCB1/P-glycoprotein Expression Influence on Non-metastatic Osteosarcoma of the Extremities

The histological response to primary chemotherapy will be expressed as a percentage of tumor necrosis. In the case of tumor necrosis above 90% the patient is defined as a "good responder" in case of a lower percentage as a "poor responder".

metastasis
localized disease
ejection fraction
adjuvant therapy
p-glycoprotein
  • 0 views
  • 19 Feb, 2024
Effect of FFRCT-angio in Functional Diagnosis of Coronary Artery Stenosis

However, the stenosis severity is not closely corresponding with the hemodynamic significance in coronary arteries. As a result, fractional flow reserve (FFR) with pressure wire measurement was introduced to functionally assess the coronary stenosis.

stenosis
hyperemia
ischemia
coronary artery stenosis
computed tomography angiography
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  • 19 Feb, 2024
Immunotherapy in Lung Cancer: Treatment After IO Cessation.

Immunotherapy is now a standard of care for first-line and eventually salvage therapy in patients with stage IV NSCLC and as adjuvant after RT-CT for stage III NSCLC. The aim of the study is determining the therapeutic landscape and the reason for immunotherapy cessation.

salvage therapy
adjuvant
small cell lung cancer
carcinoma of the cervix
chemoradiotherapy
  • 0 views
  • 19 Feb, 2024