Found 1234 clinical trials
Anaesthesia and Apoptosis
Anesthetics cause widespread apoptosis in the developing brain, resulting in neurocognitive abnormalities. However, it is unknown whether anesthesia-induced neurotoxicity occurs in humans because there is currently no modality to assess for neuronal apoptosis in vivo
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- 19 Feb, 2024
Anaesthesia and Tryptophan Pathway
Surgery has many immunomodulatory properties of which the mechanism is not clearly understood.
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- 19 Feb, 2024
Laryngomicrosurgery Under NIDP General Anesthesia Supported by THRIVE
Laryngomicrosurgery requires deep paralysis and general anesthesia to finish the procedure. After the procedure, patients need a long time to recover. In the present study, with the support of the transnasal humidified rapid-insufflation ventilatory exchange, laryngomicrosurgery would be finished under nonintubated deep paralysis (NIDP) general anesthesia.
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- 19 Feb, 2024
The Influence of Two Different CO2 Absorbers on Sevoflurane Consumption During Anaesthesia
In this study, we were interested if (i) the use of Amsorb Plus leads to a reduction in sevoflurane usage and therefore contribute to a reduction in the CO2 footprint of general anaesthesia with sevoflurane, (ii) Does the use of Amsorb Plus lead to a reduction in the amount of …
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- 19 Feb, 2024
Safety and Feasibility of Sutureless Pars-plana Vitrectomy in Sub-Tenon Anesthesia
The aim of this prospective study is to investigate the feasibility of performing minimally invasive vitrectomy under sub-tenon anesthesia in terms of intraoperative patients' tolerance and the surgeon's confidence. In particular, the tolerance and pain sensation during the operation as well as the possible perception of light and colour sensations …
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- 19 Feb, 2024
Pediatric Ultrasound-guided Dorsal Penile Nerve Block Plus Sedation in Spontaneous Breathing
One of the most frequent surgical procedures in the pediatric population is circumcision, following which postoperative pain could be stressful. Usually, the most common approach is combining regional anesthesia techniques such as landmark dorsal penile nerve block (DPNB) with general anesthesia (GA). The hypothesis of this study investigates ultrasound-guided DPNB …
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- 19 Feb, 2024
Comparison of Rocuronium Induced Neuromuscular Blockade in Late Second Trimester Pregnant and Non-pregnant Women
The present study is to compare the onset and duration of rocuronium in late second trimester women and non-pregnant women undergoing general anesthesia.
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- 19 Feb, 2024
Population at Risk of Malignant Hyperthermia: Ambispective Cohort.
Malignant hyperthermia (MH) is a pharmacogenetic disease that manifests itself as a hypermetabolic response of skeletal musculature, in genetically susceptible patients, with the inhalation of volatile halogenated anesthetics, depolarizing neuromuscular relaxants such and, rarely, physical stressors such as intense exercise and heat stroke. HM diagnosis is based on the performance …
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- 19 Feb, 2024
Frailty Anesthesia and Complications.
Objectives: To assess the prevalence of frailty in patients older than 70 y/o in nephrourologic surgery. To study if preoperative frailty is an independent predictor of immediate postoperative complications, after 30 days, 6 months and 1 year of follow-up. To detect if there are other independent risk factors for complications.
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- 19 Feb, 2024
The PAWS-COVID-19 (Pediatric AirWay complicationS COVID-19) Registry
The COVID-19 pandemic has disrupted anesthesia care all over the world. There remains very little data on current practice patterns and patient outcomes, particularly in anesthetized children.
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- 19 Feb, 2024