Found 483 clinical trials
Venetoclax SL-401 and Chemotherapy for the Treatment of Blastic Plasmacytoid Dendritic Cell Neoplasm
This phase II trial studies how well venetoclax, SL-401, and chemotherapy works in treating patients with blastic plasmacytoid dendritic cell neoplasm. Venetoclax may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. SL-401 is a recombinant protein consisting of IL-3 linked to a …
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- 19 Feb, 2024
Improving Uptake of Genetic Cancer Risk Assessment in African American Women- Video
Genetic counseling and testing (GCT) provides invaluable information for women who are at-risk of hereditary breast and/or ovarian cancer (HBOC). Black women underutilize GCT compared to White women. This study will conduct a RCT to test the efficacy of a culturally-tailored theory-based video intervention aimed to address key psychosocial factors …
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- 19 Feb, 2024
Nivolumab in Combination With TACE/TAE for Patients With Intermediate Stage HCC
This study evaluates the addition of nivolumab to TACE/TAE in the treatment of patients with intermediate stage hepatocellular carcinoma. All patients will receive TACE/TAE and half will receive nivolumab.
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- 19 Feb, 2024
ZYNRELEF® for Postoperative Analgesia After Laparoscopic Sleeve Gastrectomy (HeronBariatric)
Group 2: 30 ml of 0.5% Ropivacaine and 10mg dexamethasone into all surgical sites and intermittent IV acetaminophen as per need till discharge.Primary Objective:To compare the efficacy and duration of analgesia achieved following the instillation of ZYNRELEF® all incision sites in addition to Ropivacaine with dexamethasone + postoperative IV acetaminophen, …
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- 19 Feb, 2024
- 2 locations
Effects of Systematic Cervical Exam Training on Labor and Delivery Care
All physicians, nurses, and nurse midwives working on Labor and Delivery will be required to complete cervical exam simulation training.
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- 19 Feb, 2024
bpMRI and Risk Based Shared Clinical Decision Making in Prostate Cancer Diagnosis
The shortcoming of the pre-biopsy prostate MRI approach is the recommendation to biopsy all men post-MRI even if there is no lesion seen in MRI, ie. risk of PCa is very low. Therefore, the primary objective of this trial is to compare if there is a difference between significant cancer …
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- 19 Feb, 2024
A Trial of Treatments to Assess the Effects on Outcome of Adults With AML and MDS Undergoing Allogeneic SCT
Three approaches to improve transplant outcome will be studied: Comparing the new pre-transplant consolidation therapy vyxeos with the standard consolidation therapy Comparing new conditioning therapies in patients under the age of 55 years Comparing new conditioning therapies in patients aged 55 and over All patients will be followed up for …
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- 19 Feb, 2024
Families Children and Teachers Thriving Together
As part of this initiative, the Center for Early Childhood Health and Development (CEHD) at NYU Langone Health is implementing services to strengthen family engagement and support parents and teachers in creating safe, nurturing and predictable environments for young children. All parents of Pre-K students in the 81 district schools …
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- 19 Feb, 2024
Study of the Factors Favoring the Transition From Prediabetes to Diabetes on Reunion Island.
This results in 3 times higher mortality linked to diabetes on Reunion Island, in particular among those under 65 years of age. Despite all the screening and prevention programs put in place, the weight of diabetic disease continues to increase in our island, and this is more accelerated than in …
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- 19 Feb, 2024
Systematic Evaluation of Ablation Techniques for Non-Paroxysmal Atrial Fibrillation.
The purpose of this study is to evaluate the safety and effectiveness of empirical posterior wall isolation (PWI), left atrial appendage electrical isolation (LAAEI) and coronary sinus isolation (CSI) when compared to pulmonary vein isolation (PVI) alone: PVI alone, PVI + PWI, PVI + PWI + LAAEI, PVI + PWI …
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- 19 Feb, 2024