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Found 201 clinical trials
Cognitive Changes and Neural Correlates After Rehabilitation of Masticatory Function in Elderly -an Intervention Study

Today in elderly tooth loss and loss of oral function is widespread, but it is an underexplored modifiable risk factor potentially contributing to the development of dementia. In this interventional study we want to investigate a "cause-effect" relationship between mastication and cognition in humans. A total of eighty (80) participants, …

mental state examination
dementia
mini-mental state examination
prosthetic rehabilitation
cognitive changes
  • 0 views
  • 19 Feb, 2024
Evaluation of an Early Support Programme in Orthophony

Prospective, interventionnal with minimal risks and constraints, multicentric, non-randomized, open study, to measure the impact of an early support programme in speech and language therapy for vulnerable children (PAPEV-ortho), in children born very prematurely or very hypotrophically, on the incidence of language and communication deficits at the corrected age of …

premature birth
intrauterine growth retardation
  • 0 views
  • 19 Feb, 2024
Early Prostate Cancer Recurrence With PSMA PET Positive Unilateral Pelvic Lesion(s)

Significant advances in molecular nuclear medicine imaging in prostate cancer have been achieved in recent years. In particular, the introduction of prostate-specific membrane antigen (PSMA) -based tracers has significantly influenced diagnostic imaging of prostate. If cancer recurs after surgical removal of the prostate, targeted PSMA PET (positron emission tomography) can …

local therapy
prostatectomy
prostate specific antigen
molecular imaging
positron emission tomography
  • 0 views
  • 19 Feb, 2024
Lutetium-177-PSMA-I&T in Oligo-metastatic Hormone Sensitive Prostate Cancer

  Radioligand therapy (RLT) using Lutetium-177 labelled PSMA is a promising new therapeutic approach to treat metastatic prostate cancer. This tumor-specific treatment is directed against prostate-specific membrane antigen (PSMA), which is overexpressed in prostate cancer cells. In the last few years, several lutetium-177 (177Lu, emitter) labeled PSMA ligands have been …

androgens
cabazitaxel
testosterone
apalutamide
abiraterone
  • 4 views
  • 19 Feb, 2024
A Home-based Physical Activity Programme for Patients With Advanced Interstitial Lung Diseases (iLiFE)

Interstitial lung diseases (ILD) are a highly incapacitating group of chronic respiratory diseases, leading to disabling symptoms and impaired capacity to perform activities of daily living and health-related quality of life (HRQoL). It is known that people with ILD are highly inactive and sedentary, and in a severe stage of …

  • 0 views
  • 19 Feb, 2024
A Study of COVID 19 Convalescent Plasma in High Risk Patients With COVID 19 Infection

Purpose of Study The purpose of this study to evaluate, the effectiveness of convalescent plasma in combatting the symptoms and effects of the coronavirus disease, COVID-19. Beyond supportive care, there are no proven treatment options for COVID-19.

fraction of inspired oxygen (fio2)
covid-19
absolute lymphocyte count
d-dimer
SARS
  • 0 views
  • 19 Feb, 2024
  • 0 views
  • 19 Feb, 2024
Prevalence of DVT or PE in Patients Infected With COVID-19 Admitted to Hospital

  • To identify patients with higher risk of deep venous thrombosis.
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    deep vein thrombosis
    covid-19
    thrombosis
    • 0 views
    • 19 Feb, 2024
    Mucopolysaccharidosis I (MPS I) Registry

    The data collected by the MPS I Registry will provide information to better characterize the natural history and progression of MPS I as well as the clinical responses of patients receiving enzyme replacement therapy, such as Aldurazyme (Recombinant Human Alpha-L-Iduronidase), or other treatment modalities.

    The objectives of the Registry …

    • 0 views
    • 19 Feb, 2024
    • 125 locations
    Pompe Disease Registry

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    myozyme
    glycogen storage disease type ii
    gaa gene
    replacement therapy
    deficiency
    • 0 views
    • 19 Feb, 2024
    • 169 locations