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Found 1304 clinical trials
The ATtune Knee Outcome Study

To accomodate dissatisfied patients with a total knee arthroplasty (TKA) and improve outcomes, several knee systems have been developed. The cemented ATTUNE TKA shows superiority over other established knee systems at short-term, abating with longer follow-up. There have been no studies reporting on the results of the uncemented version of …

joint replacement
osteoarthritis
total knee replacement
  • 0 views
  • 19 Feb, 2024
PROtocol of Metabolic and Cryptogenic livEr Disease regisTry for intEgration of Omic Studies

The main aim of the study is to set up an observational cohort with NAFLD (Non-alcoholic fatty liver disease) at different stage of disease (from simple steatosis to cirrhosis and/or HCC-Hepatocellular carcinoma) and for comparative purpose a cohort of subjects with diabetes and/or obesity and/or other risk factors (i.e. psoriasis, …

psoriasis
dyslipidemia
carcinoma
metabolic syndrome
hcv infection
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  • 19 Feb, 2024
Registry for Invasive and Non-invasive Anatomical Assessment and Outcome of Coronary Artery Anomalies

An anomalous coronary artery from the opposite sinus of Valsalva (ACAOS) represents a congenital disorder with an anomalous location and/or course of the coronary vessel. The prevalence of ACAOS in the general population is around 1 % and they are mostly clinically insignificant and remain often undetected. However, some variants …

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  • 19 Feb, 2024
Finding Out if COVID-19 Infection Can be pREdicted by ChAnges in Smell and/or Taste

The FORECAST Study is an observational cohort study looking at two cohorts of patients presenting with COVID-19: a general public cohort, aiming to investigate if new loss or reduced sense of smell and/or taste are early signs of COVID-19 and a hospital cohort, which will investigate if taste/smell changes can …

covid-19
hyposmia
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  • 19 Feb, 2024
Optimizing Y90 Therapy for Radiation Lobectomy

There will be 2 Patient Groups. The first group of patients will be treated with Y90 dose and embolic load as per standard-of-care. The second group of patients will be treated with the optimal Y90 dose and embolic load found in Patient Group 1.

liver disease
liver diseases
angiography
radioembolization
hepatectomy
  • 0 views
  • 19 Feb, 2024
Virtual Anatomical Reconstruction of Mandibular Bone Defects Using a Statistical Shape Model

Hundred already taken CT-scans (50 male and 50 female) will be anonymized. These scans will be segmented and implemented into a statistical shape model that will be used to predict missing hard tissue of a mandible based on the remaining bone.

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  • 19 Feb, 2024
Glucose Monitoring During Chemotherapy

Each patch lasts for about 2-weeks. During chemotherapy visits, new patches will be placed and will be worn until the chemotherapy course is complete. Participants will be in this study for 6 months. Approximately 50 patients will be enrolled in this study.

breast cancer
immunostimulant
adjuvant
cancer
immunomodulators
  • 0 views
  • 19 Feb, 2024
Factors Affecting Outcome of Vestibular Rehabilitation

Consecutive patients (n=260) who enter the vestibular rehabilitation programme at Guy's Hospital, London will be included. Questionnaires will be conducted immediately before, and after their final treatment. The main outcome will be the Dizziness Handicap Inventory after rehabilitation.

dizziness
vestibular rehabilitation
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  • 19 Feb, 2024
Characterizing the Cross-sectional Approach to Investigate the Prevalence of Tissue BRCA1/2 Mutations in Newly Diagnosed Advanced Ovarian Cancer Patients

Patients with newly diagnosed FIGO stage III - IV advanced OC will be enrolled sequentially. In this study, data of 200 subjects will be collected at approximately 20 sites in Japan. To reduce regional bias of study sites, the number of enrolled patients per site will be capped

formalin-fixed paraffin-embedded
metastasis
cancer
primary peritoneal carcinoma
BRCA1/2
  • 0 views
  • 19 Feb, 2024
Acute Infection in Mitochondrial Disease: Metabolism Infection and Immunity During the COVID19 Pandemic

Participants genetic data will be put into a database. The data will be labeled with a code and not their name. The data will be shared with other researchers. Participation lasts about 1 year.

muscle biopsy
fatigue
sore throat
rare diseases
covid-19
  • 0 views
  • 19 Feb, 2024