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Found 201 clinical trials
Pilot Study of Performance Status 2 vs. Performance Status 0-1 Non-small Cell Lung Cancer Patients Treated With Chemo/Immunotherapy

This pilot study is configured as a non-inferiority comparison of Performance Status 2 patients with Performance Status 0-1 patients, with the goal of demonstrating non-inferiority in terms of efficacy (progression-free survival, overall survival) and safety (rates of adverse events, quality of life) when treating Performance Status 2 patients with the …

pembrolizumab
small cell lung cancer
paclitaxel
dyspnea
neutrophil count
  • 0 views
  • 19 Feb, 2024
Single- vs. Two-Fraction Spine Stereotactic Radiosurgery for the Treatment of Vertebral Metastases

Spine radiosurgery (SRS) utilizes advanced treatment planning with focused x-rays to deliver one to four high dose treatments to the spine to help relieve pain and/or neurologic symptoms. Spine SRS uses special equipment to position the participant and guide the focused beams toward the area to be treated and away …

external beam radiation therapy
karnofsky performance status
compression fracture
stereotactic radiosurgery
soft tissue sarcomas
  • 0 views
  • 19 Feb, 2024
Pilot Study of the Haymakers for Hope Fitness Program

This research study is assessing the effect of an exercise program on cancer survivors. The exercise program is Haymakers for Hope 16-week exercise program

melanoma
myocardial infarction
brain metastasis
skin cancer
cancer diagnosis
  • 0 views
  • 19 Feb, 2024
Evaluation of AZD8154 Concentrations in Blood

This study is intended to evaluate the systemic pharmacokinetic (PK) characteristics and the safety of AZD8154 following administration of the Monodose DPI formulation compared with the administration of the nebuliser suspension.

forced expiratory volume
oophorectomy
hormone level
hysterectomy
bilateral salpingectomy
  • 0 views
  • 19 Feb, 2024
Activity and Safety of Peptide-based Immunotherapy in Patients With Squamous Cell Carcinoma of the Head and Neck.

The purpose of this project is to realize a randomized open-label study (EudraCT number: 2020-000120-19) to evaluate the safety and the anti-tumor activity of peptide(s)-based immunotherapy in an umbrella window pre-operative opportunity phase II study in patients with squamous cell carcinoma of the head and neck.

head and neck carcinoma
second malignancy
neutrophil count
skin cancer
carcinoma in situ of cervix
  • 0 views
  • 19 Feb, 2024
Illusory Movements in Patients With Burns

Background. Large burns are the cause of extensive skeletal muscle devastation. The possibilities of rehabilitation of such patients are very limited, which contributes to the risk of metabolic failure and long-term musculoskeletal disorders. Illusory movements are a relatively new method of physiotherapy, which through functional proprioceptive stimulation enables the integration …

insulin
insulin resistance
musculoskeletal disorders
catabolic state
  • 0 views
  • 19 Feb, 2024
Bosutinib in Pediatric Patients With Newly Diagnosed Chronic Phase or Resistant/Intolerant Ph + Chronic Myeloid Leukemia"

This is a Phase 1-2, multicenter, international, single-arm, open-label study designed to identify a recommended dose of bosutinib administered orally once daily in pediatric patients with newly diagnosed chronic phase Ph+ CML (ND CML) and pediatric patients with Ph+CML who have received at least one prior TKI therapy (R/I CML), …

hydroxyurea
molecular diagnosis
stem cell transplantation
t315i mutation
blastic phase chronic myeloid leukemia
  • 0 views
  • 19 Feb, 2024
Cetuximab After Immunotherapy for the Treatment of Head and Neck Squamous Cell Cancer

This is a Phase II treatment, non-randomized, open label clinical trial to study the efficacy of the Cetuximab when administered as single agent in recurrent/ metastatic head and neck squamous cell carcinoma after the failure or intolerance of immuno-oncology or immuno-oncology combined with chemotherapy.

head and neck cancer
metastatic head and neck squamous cell carcinoma
cancer of the head
recurrent head and neck squamous cell carcinoma
pd-1 inhibitor
  • 0 views
  • 19 Feb, 2024
Cysteamine for Asthma

The purpose of this study is to see if a medicine called Cysteamine, given along with standard asthma care, will improve asthma symptoms and lung function.

eosinophil count
skin prick test
allergen
rhinitis
pulmonary function test
  • 14 views
  • 20 Sep, 2024
  • 1 location
Effect of Cannula Size on Oxygen Saturation During Nasal High Flow Therapy in Newborns

Treatment with nasal high flow therapy (NHF) is an increasingly popular method of respiratory support in newborns. Safe and effective use of NHF requires selection of an appropriate nasal prong-to-nares ratio because leak can influence the delivered pressure. To the best of our knowledge, this is the first study to …

  • 0 views
  • 19 Feb, 2024