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Found 123 clinical trials
High-resolution MRI (7 Tesla) of the Cervical Spine in Asymptomatic Individuals

High-resolution MRI (7 Tesla) of the cervical spine is capable to provide good differentiation between nerve and surrounding tissues within foramen und allows to reliably quantify the diameter of nerve roots/ganglia.

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  • 19 Feb, 2024
Multimodal Imaging in the Study of Disorientation in the Hospital

The purpose of this study is to investigate whether markers of brain structure and function from MRI are associated with different levels of spatial orientation and gait parameters in people with mild cognitive impairment or dementia due to Alzheimer's disease when walking through a real world environment.

cognitive impairment
dementia
alzheimer's disease
confusion
mental state examination
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  • 19 Feb, 2024
Prognostic Factors to Regain Consciousness

At study entry, different routine data, disease severity and functional status are documented for each patient. In addition, MRI, EEG and evoked potentials are measured within the first week. The level of consciousness is recorded with the Coma-Recovery-Scale-Revised and serves as the primary outcome parameter.

neurological rehabilitation
hypoxia
coma
stroke
disorders of consciousness
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  • 19 Feb, 2024
Marker Driven Selection of Patients for Prostate Biopsy and Management

The purpose of this research study is to determine if the interpretation of multiparametric MRI (mpMRI) with an algorithm called habitat risk score (HRS) in combination with a panel of blood biomarkers is more effective at detecting prostate cancer than standard of care interpretation of mpMRI with the Prostate Imaging …

digital rectal exam
tumor markers
testosterone
biopsy of prostate
digital rectal examination
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  • 19 Feb, 2024
PJ-011726 IntelliSpace Cognition MCI Study

The investigators will explore and derive correlations between parameters from routine MRI images and brain volumetric analysis and the digital cognitive data to identify parameters that are relevant to classify MCI patients vs preexisting healthy control data.

cognitive assessment
cognitive impairment
mild cognitive impairment
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  • 19 Feb, 2024
Epileptic Activity in Patients With Alzheimer's Disease and Lewy Body Dementia

Furthermore, the investigators want to investigate whether there is an association between subclinical epileptic activity and the cerebral blood flow as measured with functional MRI.

lewy body dementia
depression
illegal drugs
selective serotonin reuptake inhibitors
functional magnetic resonance imaging
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  • 19 Feb, 2024
RadioPathomics Artificial Intelligence Model to Predict nCRT Response in Locally Advanced Rectal Cancer

By the system, whether the participants achieve the pathologic complete response (pCR) will be identified based on the radiopathomics features extracted from the pre-nCRT Magnetic Resonance Imaging (MRI) and biopsy images. The predictive power to discriminate the pCR individuals from non-pCR patients, will be validated in this multicenter, prospective clinical …

chemoradiotherapy
fluorouracil
adenocarcinoma of rectum
adjuvant chemotherapy
adjuvant
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  • 19 Feb, 2024
Clinical Manifestations and Biomarkers in Amyotrophic Lateral Sclerosis Type 4 and Other Inherited Neurological Disorders of RNA Processing

They will get earplugs. The DEXA scan uses x-rays to take pictures. MRI and DEXA will be used to measure muscle, fat, and lean body mass. ...

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  • 19 Feb, 2024
Radiomics-based Artificial Intelligence System to Predict Neoadjuvant Treatment Response in Rectal Cancer

Previously, the radiomics prediction model has been constructed based on the radiomics features extracted from pretreatment Magnetic Resonance Imaging (MRI) in the training set, and optimized in the external validation set. The predictive power of this radiomics prediction model to discriminate the pathologic complete response (pCR) patients from non-pCR individuals, …

chemoradiotherapy
fluorouracil
adenocarcinoma of rectum
adjuvant chemotherapy
adjuvant
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  • 19 Feb, 2024
Prospective Trial for the Evaluation of Radiogenomics in Advanced Rectal Cancer

In patients with advanced rectal cancer, molecular subtypes will be identified by preoperative biopsy, CT, MRI / PET radiomics analysis, clinical features, and clinical features will be confirmed and compared. Also, we want to confirm the relationship between these factors and the treatment response after chemoradiotherapy before surgery.

rectal cancer
cancer
chemoradiotherapy
  • 0 views
  • 19 Feb, 2024