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Found 1102 clinical trials
A Study of SGN-B6A in Advanced Solid Tumors

It will also study whether SGN-B6A works to treat solid tumors. The study will have two parts. Part A of the study will find out how much SGN-B6A should be given to participants. Part B will use the dose found in Part A to find out how safe SGN-B6A is …

pancreatic adenocarcinoma
measurable disease
esophageal cancer
cancer, ovarian
ovarian cancer
  • 0 views
  • 19 Feb, 2024
  • 3 locations
IBI3014 in Participants With Unresectable Locally Advanced or Metastatic Solid Tumors

This is a phase 1/2 multicenter, multi-regional, open-label, first-in-human study of IBI3014 in participants with unresectable locally advanced or metastatic solid tumors.

  • 0 views
  • 22 Aug, 2025
  • 2 locations
A Study of SY 5609 a Selective CDK7 Inhibitor in Advanced Solid Tumors

This is a dose escalation study and will be the first to administer SY-5609 alone to humans with select advanced solid tumors and in combination with Fulvestrant to patients with HR positive, HER2-negative breast cancer.

measurable disease
solid tumor
stage iv breast cancer
gonadotropin
human chorionic gonadotropin
  • 0 views
  • 19 Feb, 2024
  • 5 locations
A Study of BPI-1178 in Patients With Advanced Solid Tumor and HR+/HER2- Breast Cancer

The purpose of this study is to evaluate the safety, efficacy and pharmacokinetics of BPI-1178 in subjects with advanced solid tumor, as well as the subjects with advanced hormone receptor-positive(HR+)/human epidermal growth factor receptor 2 negative (HER2-) breast cancer.

erbb1
measurable disease
solid tumor
stage iv breast cancer
letrozole
  • 0 views
  • 19 Feb, 2024
  • 1 location
Avelumab and M6620 for the Treatment of DDR Deficient Metastatic or Unresectable Solid Tumors

Giving avelumab together with M6620 may help to control DDR deficient metastatic or unresectable solid tumors.

ATR
measurable disease
fancc
estrogen
avelumab
  • 0 views
  • 19 Feb, 2024
  • 1 location
Study of Seribantumab in Adult Patients With NRG1 Gene Fusion Positive Advanced Solid Tumors

This study is an open-label, international, multi-center, Phase 2 study in adult patients with recurrent, locally-advanced or metastatic solid tumors, which harbor the NRG1 gene fusion.

formalin-fixed paraffin-embedded
solid tumor
blood transfusion
seribantumab
solid tumour
  • 0 views
  • 19 Feb, 2024
  • 1 location
Clinical Trial to Evaluate AB011 Injection in Patients With CLDN18.2-positive Advanced Solid Tumors

This is an open, two-stage, phase I study to evaluate the safety, tolerability, pharmacokinetics and preliminary efficacy of AB011 injection in patients with CLDN18.2-positive advanced solid tumors.

solid tumour
treatment regimen
solid neoplasm
  • 0 views
  • 19 Feb, 2024
  • 1 location
A First-in-human Study Using BDC-1001 in Advanced and HER2-Expressing Solid Tumors

A first-in-human study using BDC-1001 in HER2 expressing advanced malignancies

advanced solid tumor
measurable disease
exhausted
solid tumor
HER2
  • 0 views
  • 19 Feb, 2024
  • 7 locations
A Safety and Tolerability Study of NC410 in Subjects With Advanced or Metastatic Solid Tumors

This research study is studying a new drug, NC410, as a possible treatment for advanced or metastatic solid tumors.

measurable disease
oophorectomy
systemic therapy
solid tumour
serum pregnancy test
  • 0 views
  • 19 Feb, 2024
  • 1 location
B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

This is a phase I, open-label, non-randomized study that will enroll pediatric and young adult research participants with relapsed or refractory non-CNS solid tumors to evaluate the safety, feasibility, and efficacy of administering T cell products derived from the research participant's blood that have been genetically modified to express a …

cetuximab
tumors in children
steroid therapy
solid tumor
cytokine release syndrome
  • 0 views
  • 19 Feb, 2024
  • 1 location