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Found 1058 clinical trials
Long-Term Follow Up of CLN6 Batten Disease Subjects Following Gene Transfer

This is a long-term safety and efficacy study in subjects with CLN6 Batten disease who previously received a single intrathecal administration of AT-GTX-501.

batten
gene therapy
ceroid lipofuscinosis
cln6
neuronal ceroid lipofuscinosis
  • 0 views
  • 19 Feb, 2024
  • 1 location
Effect of COVID-19 on Platelet Aggregation

This is a mechanistic, observational, prospective, case and control study, to compare platelet aggregation, analyzed by Multiplate-ADP, in hospitalized patients diagnosed with COVID-19 versus healthy controls. Thus will be included 50 patients who present with respiratory symptoms within 72 hours of hospitalization and confirmation of the diagnosis of COVID-19 by …

respiratory symptom
SARS
platelet aggregation
hypertension
chronic disease
  • 0 views
  • 19 Feb, 2024
  • 1 location
Different Susceptibility to SARS CoV-2 Infection Among Health Care Workers Highly Exposed to COVID-19.

The primary objective of this study is to establish differences in susceptibility to SARS CoV-2 infection among health care workers (HCW) highly exposed to patients with COVID-19 diagnosis. To ascertain this issue, we evaluated: Changes in receptor polymorphism (ACE2 and CD26 receptor study. SARS-CoV-2 CD4/CD8 T cell response (CTL) Different …

  • 0 views
  • 19 Feb, 2024
  • 1 location
Effect of Oxalate and Urate Metabolism on CKD Evolution

The current study primarily aimed to characterize the oxalate and uric acid metabolism in CKD patients and to analyze its association with renal survival prognosis. Secondarily, the study is planned to determine whether hyperoxalemia and hyperuricemia are independent risk factors for cardiovascular events and mortality.

oxalate
Uric Acid Test
chronic kidney disease
antibiotics
hyperuricemia
  • 0 views
  • 19 Feb, 2024
  • 1 location
Asthma: Phenotyping Exacerbations 2

The main outcomes of this study are to establish a cohort of well-phenotyped asthma patients with a recent history of an exacerbation. We aim to describe exacerbation profiles (phenotypes) of the cohort in terms of inflammatory/biomarker profile and bacterial/viral infection status and to compare these with exacerbation events in the …

skin prick
maintenance therapy
corticosteroids
spirometry
prick skin
  • 0 views
  • 24 Nov, 2025
  • 1 location
Asthma: Phenotyping EXacerbations

The main outcomes of this study are to establish a cohort of well-phenotyped asthma patients with a recent history of an exacerbation. We aim to describe exacerbation profiles (phenotypes) of the cohort in terms of inflammatory/biomarker profile and bacterial/viral infection status and to compare these with exacerbation events in the …

skin prick
maintenance therapy
corticosteroids
spirometry
prick skin
  • 0 views
  • 19 Feb, 2024
  • 1 location
Long-Term Prospective Registry in Prostate Cancer Patients From Diverse Urology Practice Settings Following Prolaris Testing

This registry will evaluate treatment selection for patients with newly diagnosed, localized prostate cancer following Prolaris testing. It will measure the proportion of men who initially select treatment with active surveillance, the time frame between active surveillance selection and any change in treatment, and clinical outcomes.

prolaris testing
adenocarcinoma of prostate
adenocarcinoma
  • 0 views
  • 19 Feb, 2024
  • 1 location
Lung Ultrasound in COVID-19 Patients

To assess the prognostic performance of an early global LUS score with respect to the mortality in ICU and duration of ventilation.

PCR test
lung ultrasound
covid-19
  • 0 views
  • 19 Feb, 2024
  • 1 location
Sex & Sleep in Athletes

Achieving the correct quantity and quality of sleep is essential for the health and recovery processes of the athlete; night rest is often negatively influenced by many variables, including: high training loads, long-range trips, evening competitions, and / or high levels of anxiety and stress. High training loads can therefore …

anxiety
  • 0 views
  • 19 Feb, 2024
  • 1 location
Trajectory of Microbiota Maturation in Healthy Bern Infants - a Network Approach

Background: Intestinal microbiota composition is fundamental to human health and undergoes critical changes within the first two years of life. Factors probably influencing the microbiota are the maternal microbiota and the general environment in Switzerland. However, the development of the intestinal microbiota is incompletely understood. Gaining knowledge of the trajectory …

microbiota
mass spectrometry
hypertension
placenta
diabetes
  • 0 views
  • 19 Feb, 2024
  • 1 location