Found 1017 clinical trials
Post-surgical Liquid Biopsy-guided Treatment of Stage III and High-risk Stage II Colon Cancer Patients: the PEGASUS Trial
PEGASUS is a prospective multi-centric study designed to prove the feasibility of using liquid biopsy to guide the post-surgical and post-adjuvant clinical management in 140 microsatellite stable Stage-III and T4N0 Stage-II colon cancer patients.
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- 19 Feb, 2024
- 9 locations
Acute Colon Resection Versus Bridge to Colon Surgery With Stent or Stoma
P patients with acute obstructive colon cancer I resection or bridge to surgery with stent or stoma C emergency procedure O morbidity and mortality within 30 days, 90 day mortality and 3 & 5 years overall survival
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- 19 Feb, 2024
- 1 location
BESPOKE Study of ctDNA Guided Therapy in Colorectal Cancer
The BESPOKE CRC study will prospectively enroll patients who have undergone surgery for stage II or III colorectal cancer (CRC) and who have residual formalin-fixed paraffin-embedded (FFPE) tissue available will provide FFPE and whole blood samples. Patients will receive SIGNATERA test results and may be recommended for adjuvant chemotherapy or …
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- 19 Feb, 2024
- 17 locations
Oxaliplatin Adjuvant Chemotherapy After Curative Resection of Primary Colon Cancer
According to general medical guidelines, adjuvant chemotherapy is used after curative resection of high-risk stage II or III primary colon cancer. However, there exist limitations using clinical trial data acquired from highly selected subjects in a controlled environment.
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- 19 Feb, 2024
- 1 location
Health and Employment After Gastro Intestinal Surgery - HEAGIS2
By using the M.A.D.I.T. methodology and the Dialogics science, SALVO Project aims to develop operational guidelines to support oncological target patients in the resumption of their daily post-operative activities. The research will implement an instrument for the purpose of measuring the health need of participants who are admitted to the …
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- 19 Feb, 2024
- 2 locations
A Prospective Single-Center Evaluation of SureForm Staplers in Robotic-assisted Colorectal Procedures
The primary objective of this study is to evaluate the performance of SureForm Staplers (60 and 45) for transection and/or creation of anastomosis during robotic-assisted colorectal procedures.
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- 19 Feb, 2024
- 1 location
Identify the Obstacles to Early Diagnosis of Cancer in Patients Over 75 Years Old on an Outpatient Basis
Cancer can be discovered suddenly: for example, occlusion with peritonitis in case of a stenosing colonic tumor, leading to urgent management. The elderly are often excluded from clinical studies. In addition, the geriatric population is heterogeneous, leading to very diverse and individual care, with prioritization of issues.
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- 19 Feb, 2024
- 3 locations