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Found 1081 clinical trials
Descriptive Study of Acute Spontaneous Spinal Cord Infarction

Differential diagnosis with other transverse myelopathy causes is a common issue. As in cerebral stroke, there are multiple causes and mechanisms in spontaneous SCI, often difficult to clearly establish. There are also clinical and radiological patterns, sometimes misleading, according to vascular territory and its expanse.

  • 0 views
  • 19 Feb, 2024
  • 1 location
The Effect and Mechanism of lncRNA NBR2 Regulating Endothelial Pyroptosis by Targeting GSDMD in Sepsis

Gasdermin D (GSDMD) mediated endothelial pyroptosis plays a critical role in modulating vascular endothelial injury in sepsis. Long non-coding RNA (lncRNA), as a class of non-coding protein RNA longer than 200 kD, contributes to a variety of cell biological processes. The dysregulation of lncRNA results in the occurrence and development …

organ failure
long non-coding rna
dysregulated host response
cell injury
septicemia
  • 0 views
  • 19 Feb, 2024
  • 1 location
Interest of a Period of Fasting Before Extubation in Resuscitation Patients

The hypothesis is that continued enteral nutrition before extubation is associated with increased gastric volume as measured by ultrasound.

resuscitation
polytrauma
mechanical ventilation
opioid
gastric ultrasound
  • 0 views
  • 19 Feb, 2024
  • 1 location
Cardiac Biomarkers in Preeclampsia: Prediction of Disease and the Risk of Future Cardiovascular Events in Survivors

Data Analysis: would be performed using the Statistical Package for Social Sciences (SPSS) software version 21.0. Numerical data would be expressed as mean standard deviation (SD). Results from the two groups of women would be compared using the independent T-test, Analysis of Variance (ANOVA) and the chi-square test while the …

stroke
atherosclerosis
sepsis
hscrp
apob
  • 0 views
  • 19 Feb, 2024
  • 1 location
Early Diagnosis of Upper Digestive Tract Disease

Exhaled breath testing is a non-invasive and acceptable technology utilising mass spectrometry (MS) which has shown promise at diagnosing cancer at an early stage. Previous research has shown that products formed as a result of metabolism can be measured in breath and saliva (biomarkers). This has the ability to accurately …

mass spectrometry
gastrointestinal disorder
early diagnosis
early detection
cancer
  • 4 views
  • 19 Feb, 2024
  • 1 location
Evaluation of the Satisfaction of Patients Coming "on Foot" in the Operating Room

In this context, the optimization of the whole patient's journey during the perioperative period has been reviewed and adapted to personalized management within healthcare facilities. For more than a year now, multimodal approaches such as early rehabilitation have been undertaken, including morning admission with an innovative principle of "3D" patient …

ambulatory surgery
anesthesia
  • 0 views
  • 19 Feb, 2024
  • 5 locations
Natural History Study of Children and Adults With Adrenocortical Cancer (ACC)

Participants home physician will be contacted every 6 to 12 months to collect medical information such as test results and scans. Participants may be asked to return to the NIH every 6 to 12 months for follow-up tests. Participants will contact study staff if there are any changes in their …

adrenocortical carcinoma
blood tests
cancer
solid tumors
adrenal
  • 0 views
  • 19 Feb, 2024
  • 1 location
Natural History Study of Children and Adults With Neuroendocrine Neoplasms (NEN)s

Participants home doctors will be contacted every 6 to 12 months. They will give medical data such as imaging and test results. Participants may have follow-up visits at NIH every 6 to 12 months. Participants will contact researchers if there are any changes in their tumor.

proinsulin
neuroendocrine tumor
cancer
vasoactive intestinal polypeptide
vasoactive intestinal peptide
  • 0 views
  • 19 Feb, 2024
  • 1 location
COVID-19 in Cancer Patients: Evaluation of Clinical Course and Impact on Oncological Care Including Biobanking

The COVIDHELP study will prospectively evaluate the yet unknown clinical course of the COVID-19 infection in cancer patients and document the impact of potential infrastructural limitations on cancer care of COVID-19 positive patients. All patients consenting will provide peripheral blood samples for prospective biobanking with the aim of investigating immune …

cancer care
covid-19
cancer
  • 0 views
  • 19 Feb, 2024
  • 1 location
Effect of Oxalate and Urate Metabolism on CKD Evolution

The current study primarily aimed to characterize the oxalate and uric acid metabolism in CKD patients and to analyze its association with renal survival prognosis. Secondarily, the study is planned to determine whether hyperoxalemia and hyperuricemia are independent risk factors for cardiovascular events and mortality.

chronic kidney disease, stage 1
hyperuricemia
antibiotics
oxalate
dialysis
  • 0 views
  • 19 Feb, 2024
  • 1 location